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Special Issue Title:

Efficacy of Medication Administered During Adult Cardiac Arrest

Deadline for manuscript submissions: 10 November 2021

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Special Issue Editor

  • Guest Editor

    Dr. Wachira WongtanasarasinE-MailWebsite

    Attending physician, Department of Emergency Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand

    Interests: Resuscitation, Cardiac arrest, Cardiopulmonary resuscitation, Critical care medicine

Special Issue Information

Cardiopulmonary resuscitation (CPR) is a complex procedure aiming to restart normal circulation and restore normal perfusion. CPR consists of basic life support (BLS) and advanced cardiac life support (ACLS). The guidelines for managing patients with cardiac arrest were first published in 1966. Since then, CPR guidelines have been reviewed and updated regularly every five years by the American Heart Association (AHA). To date, the AHA recommended only three medications in the algorithms, consisted of epinephrine (adrenaline), amiodarone, and lidocaine. However, recent literatures have been reported that there were several medications as well as non-pharmacological interventions that ameliorate the outcomes of CPR (i.e., bicarbonate, calcium, vasopressin, steroid). Despite the guidelines stated that acidosis (H+) is one of the reversible causes of cardiac arrest, bicarbonate, which makes blood more alkali, is not routinely recommended. Besides, calcium represents another example of this controversy. Despite stating that hyperkalemia is the reversible cause of cardiac arrest, calcium, which is recommended for stabilizing myocardial membrane potential during hyperkalemia, is not routinely recommended, as well. The debate on these topics is continuing. As a result, this special issue is conducted.

The goal of this special issue is to enhance the evidence regarding the use of medications and non-pharmacological interventions during adult cardiac arrest. As one of the greatest scientists, Albert Einstein, said, if you want different results than what you are getting, you have to try different approaches. We have the CPR guidelines for over 50 years; however, the rate of favorable neurological outcomes after attempted resuscitation is still the same. Like most things in life, you may not always succeed, but failure is usually guaranteed if you do not try.


Cardiac arrest, Cardiopulmonary resuscitation, CPR, Advanced life support, Medication, Emergency medicine, Resuscitation, Bicarbonate, Calcium, Steroid

Manuscript Submission Information

Manuscripts should be submitted online by submit system. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Original articles, case reports or comprehensive reviews are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website. Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Signa Viate is an international peer-reviewed open access journal published by MRE Press. As of January 2021, Signa Vitae will change to a bimonthly journal. Please visit the Instructions for Authors page before submitting a manuscript.The Article Processing Charge (APC) for publication in this open access journal is $1200. We normally offer a discount greater than 30% to all contributors invited by the Editor-in-Chief, Guest Editor (GE) and Editorial board member. Submitted papers should be well formatted and use good English.

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Published Papers (1 papers)

Open Access Special Issue

Effect of prehospital intraosseous combined with in-hospital intravenous access in out-of-hospital cardiac arrest

Yan-Wei Cheng,Jian-Ge Zhang,Xue Cao,Juan Zhu,Li-Jie Qin

Online publish date: 17 March 2021

DOI: 10.22514/sv.2021.046

Abstract ( 291 ) PDF (338.41 kB) ( 153 )

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