Aims and scope

The aim of Signa Vitae (SV) is to be an unbiased and permanent forum for clinical anesthesia, intensive care, emergency and pain medicine. It serves professionals dedicated to all these relevant fields, as a tool for easier and more effective experiences and science sharing, with the ultimate goal to improve patients’ outcome. The scope of Signa Vitae is broad. It encompasses all aspects of clinical practice and research at the basis of anesthesia, intensive care, emergency and pain medicine, both in children and adults. It will better inform and educate the global scientific and medical community on the advancements in the fields at the basis of survival and a better quality of life, as stated in the appealing Latin version of its name: "Signs of life". 


Open Access

Four pandemics: lessons learned, lessons lost

Joseph V. Pergolizzi,Jo Ann LeQuang,Robert Taylor,Charles Wollmuth,Meghan Nalamachu,Giustino Varrassi,Paul Christo,Franklin Breve,Peter Magnusson

DOI: 10.22514/sv.2020.16.0096

Abstract ( 549 ) PDF (182.28 kB) ( 47 )

Open Access

Performing General Surgery Emergencies Safely during COVID-19 Outbreak

Ozlem Zeliha Sert,Sevcan Alkan Kayaoglu

DOI: 10.22514/sv.2020.16.0077

Abstract ( 233 ) PDF (190.88 kB) ( 20 )

Open Access

Factors Affecting Return Visits to the Emergency Department within 30 Days

Aušra Bilotienė Motiejūnienė,Andrius Klimašauskas,Eglė Kontrimavičiūtė,Eugenijus Jasiūnas,Rūta Janulevičienė,Dovilė Majauskytė,Rimantas Stukas

DOI: 10.22514/sv.2020.16.0080

Abstract ( 269 ) PDF (206.97 kB) ( 35 )

Open Access

Emergency Department Length of Stay for Critically Ill Patients Followed Up in Red Zone

Fatih Cakmak,Ibrahim Ikizceli,Derya Ozturk,Ertugrul Altinbilek,Banu KarakusYilmaz,Serap Biberoglu,Ahmet Oluk,Ahmet Cevdet Toksoz

DOI: 10.22514/sv.2020.16.0048

Abstract ( 286 ) PDF (187.51 kB) ( 33 )

Open Access

Sudden cardiac arrest pharmacotherapy with prefilled syringes improves adherence to Advanced Life Support protocol in understaffed resuscitation pre-hospital care teams

Radoslaw Zalewski,Wojciech Telec,Mateusz Puslecki,Marek Dabrowski,Bartlomiej Perek,Lukasz Szarpak

DOI: 10.22514/sv.2020.16.0098

Abstract ( 360 ) PDF (1.01 MB) ( 23 )

Open Access

Incidental appendiceal neoplasias: ten years' experience with 1,642 patients

Server Sezgin Uludag,Nazim Gures,Abdullah Kagan Zengin

DOI: 10.22514/sv.2020.16.0093

Abstract ( 143 ) PDF (3.96 MB) ( 16 )

Open Access

Automatic compression improves adherence to advanced life support protocol in two-paramedic team. A randomized simulation study

Tomasz Kłosiewicz,Mateusz Puślecki,Łukasz Szarpak,Marek Dąbrowski,Bartłomiej Perek

DOI: 10.22514/sv.2020.16.0110

Abstract ( 124 ) PDF (742.91 kB) ( 24 )

Open Access

Anesthetic Management of Patients Undergoing Renal Transplantation: A Review of A Two-year Experience

Burhan Dost,Muzeyyen Beldagli,Cengiz Kaya,Yasemin Burcu Ustun,Sezgin Bilgin,Ersin Koksal,Yakup Bostancı

DOI: 10.22514/sv.2020.16.0078

Abstract ( 302 ) PDF (192.45 kB) ( 39 )

Open Access Special Issue

Establishment of a Linear Correlation Model of Central Venous Blood Oxygen Saturation and Lactate in Sepsis

Songchang Shi,Xiaobin Pan,Wei Lin,Chao Wu,Mei Ye,Yingfeng Zhuang,Jian Lin,Xincai Wang,Lihui Zhang,Shujuan Zhang,Hangwei Feng,Long Huang,Songjing Shi,Xingsheng Lin

DOI: 10.22514/sv.2020.16.0064

Abstract ( 218 ) PDF (2.34 MB) ( 23 )

Open Access

Prognostic Factors in Obturator Hernia

Semra Salimoğlu,Semra Demirli Atıcı

DOI: 10.22514/sv.2020.16.0038

Abstract ( 328 ) PDF (354.89 kB) ( 33 )

Open Access

Validity of Signal Peptide-CUB-EGF Domain-containing Protein-1 (SCUBE-1) in the Diagnosis of Aortic Dissection

Adem Çakır,Umut Payza,Saliha Aksun,Ahmet Kayalı,Zeynep Karakaya,Fatih Esad Topal

DOI: 10.22514/sv.2020.16.0043

Abstract ( 292 ) PDF (215.83 kB) ( 32 )

Open Access

Post-operative respiratory outcomes associated with the use of sugammadex in laparoscopic colorectal cancer surgery: a retrospective, propensity score matched cohort study

Chahyun Oh,Yumin Jo,Seojin Sim,Sangwon Yun,Seungbin Jeon,Woosuk Chung,Seok-Hwa Yoon,Chaeseong Lim,Boohwi Hong

DOI: 10.22514/sv.2020.16.0116

Abstract ( 215 ) PDF (268.03 kB) ( 13 )

Open Access

The New Markers of Ventricular Dispersion in Patients with Acute Poisoning with TCAs: Tp-e Interval and Tp-e/QTc Ratio

Akkan Avci,Mehmet Uzucek,Satuk BugraYapici,Begum Seyda Avci,Onder Yesiloglu,Hayri Cinar,Ferhat Icme,Salim Satar

DOI: 10.22514/sv.2020.16.0044

Abstract ( 245 ) PDF (222.25 kB) ( 30 )

Open Access Special Issue

Use of Ultrasound for Diagnosis of Clavicle Fractures in the Emergency Department

Sinan Karacabey,Erkman Sanrı

DOI: 10.22514/sv.2020.16.0046

Abstract ( 335 ) PDF (281.45 kB) ( 31 )

Open Access

Risk factors for neurological complications and clinical outcomes in patients with left ventricular assist devices

Meltem Songur Kodik,Ali Kemal Yildiz,Ilhan Uz,Sercan Yalçinli,Umit Kahraman,Elif Bolat,Ayşe Guler,Cenk Eraslan,Yusuf Ali Altunci

DOI: 10.22514/sv.2020.16.0114

Abstract ( 192 ) PDF (413.17 kB) ( 19 )

Open Access

Pharmacological Interventions for Post-operative Sore Throat (POST): A Network Meta-analysis

Rakan M. AlQahtani,Mohyeldin Abdalla,Yamen Hassan Azzam,Ahmed AbdElhamed Elsherif,Raed Ibrahim Altulayhi

DOI: 10.22514/sv.2020.16.0085

Abstract ( 201 ) PDF (930.39 kB) ( 23 )

Open Access

Zombie deer and the species barrier. Should humans worry about it?

Joseph V. Pergolizzi,Giustino Varrassi,Jo Ann LeQuang

DOI: 10.22514/sv.2020.16.0092

Abstract ( 495 ) PDF (141.06 kB) ( 32 )

Open Access

Gastric Outlet Obstruction Due to Cholecysto-Gastric Fistula: Bouveret’s Syndrome

Savas Sezik,Mustafa Sever,Nezih Kavak,Ahmet Burak Erdem

DOI: 10.22514/sv.2020.16.0036

Abstract ( 327 ) PDF (2.79 MB) ( 29 )

Published Ahead of Print

Open Access

Determinants of complications in first ever acute stroke patients: a prospective observational study from India

Vishal Madhukar Sawale,Durjoy Lahiri,Ritwik Ghosh,Souvik Dubey,Gautam Das,Goutam Gangopadhyay,Biman Kanti Ray

Online publish date: 12 January 2021

DOI: 10.22514/sv.2021.002

Abstract ( 48 ) PDF (218.28 kB) ( 3 )

Open Access

Antioxidative activity of statins and HDL-PON1 association in lacunar ischemic stroke with and without white matter hyperintensity

Hyun Goo Kang,Jin Sung Cheong,In Hwan Lim,Kyeong Ho Yun,Hyun Young Park

Online publish date: 12 January 2021

DOI: 10.22514/sv.2021.003

Abstract ( 41 ) PDF (426.42 kB) ( 4 )

Open Access

Should we screen patients' relatives for psychological status, signs and symptoms in the emergency department? A cross-sectional survey using the Symptom Check List (SCL-90)

Mandana Hosseinzadeh,Ozgur Karcioglu,Ibrahim Ikizceli,Fatih Cakmak,Asghar Kolahforoush

Online publish date: 12 January 2021

DOI: 10.22514/sv.2021.004

Abstract ( 45 ) PDF (192.49 kB) ( 4 )

Open Access

Changes in hemodynamic parameters with the use of etomidate versus ketamine induction in the emergency department

Abdullah Bakhsh,Maryam Alnashri,Fatimah Alawami,Rafal Aseel,Maha Almaghthawi,Ghaida Alrahaili,Anas Bifari,Hassan Algethami

Online publish date: 12 January 2021

DOI: 10.22514/sv.2021.005

Abstract ( 73 ) PDF (570.36 kB) ( 13 )

Open Access

Application status of the definition of polytrauma in clinical research-A review of the past decade

Ding Xu,Yu-Long Shi,Peng Luo,Wei-Jun Guo

Online publish date: 07 January 2021

DOI: 10.22514/sv.2020.16.0120

Abstract ( 118 ) PDF (374.35 kB) ( 16 )

Open Access

Dysmenorrhea is associated with a higher incidence of pain after diagnostic hysteroscopy or treatment

Yuan-Yuan Pan,Shen-Hui Jin,Shan Luo,Ru-Ru Li,Ying-Ying Tu,Dan Jin,Wen-Jun Jin,Xiu-Xiu Zhuang,Jun-Lu Wang

Online publish date: 04 January 2021

DOI: 10.22514/sv.2020.16.0117

Abstract ( 108 ) PDF (249.8 kB) ( 19 )

Special Issues

Special issue title:

Therapeutic hypothermia or targeted temperature management in the treatment of cardiac arrest and other life-threatening conditions

Keywords: Cardiac arrest, Therapeutic hypothermia, Adverse effects, Targeted temperature management, Intracranial hemorrhage, Resuscitation

Editor: Dr. Ozgur KARCIOGLU

Submission deadline: 10 December 2021

Special issue title:

Exosomes and Delayed Encephalopathy After Acute Carbon Monoxide Poisoning (DEACMP)

Keywords: Acute CO poisoning, DEACMP, Exosomes

Editor: Dr. Yuan Jiang

Submission deadline: 15 September 2021

Special issue title:

Cardiopulmonary Resuscitation: The Array of Therapuetic Approaches

Keywords: Cardiopulmonary arrest, Resuscitation, Resuscitation training, Survival to discharge, Survival to admission, Neurologic recovery

Editor: Dr. Abdullah Bakhsh

Submission deadline: 15 September 2021

Special issue title:

Out-of-Hospital Cardiac Arrest (OHCA)

Keywords: Out-of-hospital cardiac arrest (OHCA), Bystander cardiopulmonary resuscitation, Post-Resuscitation care, Automated external defibrillator (AED), Target temperature management (TTM)

Editor: Dr. Chien-Yu Chien,Dr. Yan-Ren Lin

Submission deadline: 15 September 2021

Special issue title:

Emergency Department Cardiac Arrest (EDCA)

Keywords: Emergency department cardiac arrest, EDCA, Emergency medicine, Resuscitation, In-hospital cardiac arrest, IHCA

Editor: Dr. Shou-Yen Chen

Submission deadline: 15 September 2021

Special issue title:

Big Data and Status Asthmaticus

Keywords: Status asthma, Big data, Big data analytics, Epidemiology

Editor: Dr. Herng-Ching Lin

Submission deadline: 31 August 2021

Special issue title:

ECMO in Emergency Department

Keywords: ECMO, Emergency department, Critically ill patient, Transportation, CPR

Editor: Dr. Young-Jae CHO

Submission deadline: 31 May 2021

Special issue title:

Acute Hydrocephalus

Keywords: Acute hydrocephalus, Pathogenesis; Therapeutic development; Intensive care; Emergency medicine; Anaesthesia

Editor: Dr. Gelei Xiao

Submission deadline: 31 July 2021

Special issue title:

Biomarkers and Action Strategies in Early and Subclinical Acute Kidney Injury

Keywords: Acute kidney injury, Acute kidney disease, Tubular damage, Biomarkers, Nephron

Editor: Dr. Yacov Shacham

Submission deadline: 31 July 2021

Latest tweets


SepsEast and COVID-19: Time to Make a Difference #COVID-19 #SepsEast

24 July 2020

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You are welcome to join our editorial board. Our journal produces and issues editorial board certificates for editorial board members, and the journal website will display the names and personal websites of editorial board members to help enhance their scientific influence. Members of the editorial committee are entitled to 2 free publications (both editorial member’s or recommended paper) per year, and other articles over 2 can enjoy 30% discount of publishing fee.

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  2020 has been a very special year, full of events, frequently strange and newly shaped events. As always, humanity has tried to learn from them, searching (and frequently finding) the best solution to the problems. “Work is the best gymnasium where to exercise the intelligence”. This was an excellent definition for “work”. 2020 has obliged anyone to work with new obstacles and to find always new solutions, exercising the intelligence. It is also possible to say that 2020 has provided mankind a fantastic opportunity to express at maximum level its potentialities.

  Between others, I was kindly invited to becoming Editor in Chief of this important journal. Signa Vitae has a nice story, but its aim is to increase its impact in the scientific community. The scientific community deriving from the initial “Anesthesiology”, as it was in the first decades of the twentieth century, in the course of the years has expanded enormously. Now it still covers “Anesthesiology”, but it also covers Emergency, Intensive Cares, Supportive Medicine, and last but not least Pain Medicine. In other terms, the name of the journal, Signa Vitae (“Signs of Life”, with a nuance of Latin classic culture), is extremely appropriate.

  Considering my personal story, the diffusion of Signa Vitae in the field of Pain Medicine will be a natural consequence. The new challenge will definitely be to establish a strong Editorial Board, with Section Editors, and attract high quality papers from the other branch of the medical specialty. For this, the journal counts on the support of most of the Members of the Editorial Board whose story is deeply rooted in Emergency and Intensive Cares.

  The programs for 2021 are incredibly challenging and stimulating. It will be a year of hard work and growth, and the Signa Vitae family is ready to obtain the best possible. I want to take this opportunity to thank the publisher and the Signa Vitae team for their trust in my enthusiasm, inviting me as Editor-in-Chief of a nice and promising journal. Ad majora to all of them and especially to the Authors that will be confident on the potentialities of this journal. Let’s work together for it.

Giustino Varrassi, MD, PhD

Paolo Procacci Foundation, Via Tacito 7, 00193 Roma, Italy