Aims and scope

The aim of the Signa Vitae (SV) journal is to act as an unbiased and permanent forum for clinical anaesthesia, intensive care and emergency medicine, to serve professionals dedicated to relevant fields, as a tool for easier and more effective knowledge and experience sharing, with the ultimate goal to improve patients’ outcome.
The scope of the Journal is broad, encompassing all aspects of the knowledge of clinical practice and the fundamental understanding of adult, pediatric and neonatal intensive care, as well as anesthesia and emergency medicine, to better inform and educate the global scientific community.


Open Access

SepsEast and COVID-19: Time to Make a Difference

Mitja Lainscak,Alan Sustic,Jan Benes,Miroslaw Czuczwar,Radmilo Jankovic,Mikhail Kirov,Roman Kula,Krzysztof Kusza,Matej Podbregar,Dorel Sandesc,Ovidiu Bedreag,Konstanty Szuldrzynski,Roman Zahorec,Peter Hegyi,Zsolt Molnar

DOI: 10.22514/sv.2020.16.0001

Abstract ( 1995 ) PDF (192.59 kB) ( 139 )

Open Access

Osteoarticular Infections in Newborns: Prognostic Factors and Outcome

Aneta Soltirovska Salamon,Spela Capuder,Damjana Kljucevsek,Karin Schara,Darja Paro-Panjan

DOI: 10.22514/sv.2020.16.0002

Abstract ( 1097 ) PDF (750.95 kB) ( 132 )

Open Access

Metronome Use Positively Affect Cardiopulmonary Resuscitation Parameters: Prospective Observational Multicenter Manikin Study

Necmiye Yalcin Ocak,Mustafa Sever,Orkun Unek,Ibrahim Toker,Emirhan Erdem,Murat Yesilaras,Ozge Duman Atilla

DOI: 10.22514/sv.2020.16.0005

Abstract ( 981 ) PDF (179.51 kB) ( 79 )

Open Access

High-flow Nasal Cannula is Superior to Standard Face-Mask Oxygen Therapy in Viral Bronchiolitis

Esra Türe,Abdullah Yazar,Fatih Akın,Sevgi Pekcan

DOI: 10.22514/sv.2020.16.0007

Abstract ( 1025 ) PDF (602.9 kB) ( 73 )

Open Access

Impact on the Regional Ambulance Services and Emergency Departments of the 2017 Freezing Rain in Milan

Giovanni Landoni,Omar Saleh,Maurizio Migliori,Carlo Picco

DOI: 10.22514/sv.2020.16.0010

Abstract ( 722 ) PDF (246.12 kB) ( 32 )

Open Access

Impact of Different Stimulation Patterns of Neuromuscular Blockade Monitoring and Clinical Assessment on Intubation Time and Intensity of Hemodynamic Response During Rocuronium Induced Endotracheal Intubation

Radmilo J. Janković,Milena D. Stojanović,Danica Z. Marković,Vladan A. Cvetanovic,Anita Z.Vuković,Aleksandar N.Nikolić,Ines S.Veselinović,Biljana S.Stošić

DOI: 10.22514/sv.2020.16.0011

Abstract ( 441 ) PDF (434.95 kB) ( 36 )

Open Access

Non-contrast Cranial Computed Tomography can Change the Emergency Management of Nontraumatic Seizure Patients

Mustafa Sever,Gulsenem Cicek,Necmiye Yalcin Ocak,Yesim Eyler,Rana Toktas,Ibrahim Toker,Murat Yesilaras

DOI: 10.22514/sv.2020.16.0014

Abstract ( 421 ) PDF (317.65 kB) ( 37 )

Open Access

Dexmedetomidine on Continuous Infraclavicular Block after Elbow Arthrolysis

Shuishui Wu,Zongjian Sun,Ronghua Li,Ling Li

DOI: 10.22514/sv.2020.16.0017

Abstract ( 479 ) PDF (207.64 kB) ( 38 )

Open Access

Prognosis of COVID-19 Patients Requiring Intensive Care Unit Care

Hülya Sungurtekin,Ülkü Arslan,Cansu Özgen,İsmail Hakkı Akbudak,Mithat Kahramanoglu,Hakan Erbay,Habip Atalay,Ahmet Çalişkan,Simay Karaduman

DOI: 10.22514/sv.2020.16.0019

Abstract ( 577 ) PDF (191.79 kB) ( 78 )

Open Access

Accuracy of Healthcare Providers' Perception of Chest Compression Depth and Chest Recoil

Sendoa Ballesteros-Peña,Gorka Vallejo-De la Hoz,Irrintzi Fernández-Aedo,Alejandro Etayo-Sancho,Leire Berasaluze-Sanz,Josune Domínguez-García

DOI: 10.22514/sv.2020.16.0021

Abstract ( 814 ) PDF (196.66 kB) ( 43 )

Open Access

The Clinical and Computed Tomography Findings of Patients with COVID-19

Afsin Ipekci,Yonca Senem Akdeniz,Onur Tutar,Sabri Sirolu,Osman Simsek,Seda Özkan

DOI: 10.22514/sv.2020.16.0023

Abstract ( 520 ) PDF (321.59 kB) ( 57 )

Open Access

Could the Implantation of Dextranomer/Hyaluronic Acid Cause the Elevation of Neuron-Specific Enolase in Children Treated for Vesicoureteral Reflux?

Iva Bilić Čače,Ana Milardović,Harry Nikolić,Ana Bosak Veršić,Ivona Butorac Ahel

DOI: 10.22514/sv.2020.16.0025

Abstract ( 443 ) PDF (155.47 kB) ( 39 )

Open Access

Recovery from Critical COVID-19 Despite Delays in Diagnosis and Respiratory Treatment: a Cautionary Tale

Ouyang Fan,Fu Qiang,Guo Shuhong,Yang Haibing,Li Xiangyang,Tang Min,Yang Li

DOI: 10.22514/sv.2020.16.0027

Abstract ( 578 ) PDF (1.26 MB) ( 79 )

Open Access

Prone Ventilation in a 27 Week Pregnant Woman with COVID-19 Severe ARDS

Luigi Barile,Martina Cerrano,Alessandro Locatelli,Andrea Puppo,Anna F. Signorile,Nicoletta Barzaghi

DOI: 10.22514/sv.2020.16.0028

Abstract ( 914 ) PDF (777.46 kB) ( 156 )

Open Access

Metoclopramide-Induced Dystonic Reaction in an Infant

Songul Tomar-Guneysu,Okşan Derinoz-Guleryuz,Ozlem Colak,Ilknur Fidanci

DOI: 10.22514/sv.2020.16.0029

Abstract ( 541 ) PDF (133.01 kB) ( 61 )


Open Access

Quality of Chest Compressions on A Dental Chair -- A Randomized Simulation Trial as Observation in Support of A Procedure Proposal

Tomasz Kłosiewicz,Mateusz Puślecki,Radosław Zalewski,Michał Mandecki,Ilona Skitek-Adamczak,Maciej Sip,Marek Dąbrowski,Martyna Ratajczak,Przemysław Rachubiński,Bogusz Szczepański,Marek Dorożyński,Beata Czarnecka,Bartłomiej Perek

Online publish date: 14 October 2020

DOI: 10.22514/sv.2020.16.0073

Abstract ( 84 ) PDF (528.05 kB) ( 9 )

Open Access

Reliability of the Pneumonia Severity Score (PSI) Index in Patients Diagnosed with COVID-19 Pneumonia to Determine Outpatient Discharge

Ahmet Burak Erdem,Hakan Oğuztürk,Miray Tümer,Bahattin Işık,Afsin Emre Kayipmaz,Semih Korkut

Online publish date: 14 October 2020

DOI: 10.22514/sv.2020.16.0074

Abstract ( 89 ) PDF (240.76 kB) ( 8 )

Open Access

Anti-inflammatory Role of Trilobatin on Lipopolysaccharide-induced Acute Lung Injury through Activation of AMPK/GSK3β-Nrf2 Pathway

Hai Zhong,Long Hao,Xiang Li,Chunjing Wang,Xu Wu

Online publish date: 14 October 2020

DOI: 10.22514/sv.2020.16.0075

Abstract ( 74 ) PDF (953.8 kB) ( 5 )

Open Access

Evaluation of Ventricular Repolarization Parameters in Patients Admitted to Emergency Department with Electrical Injury

Çaşıt Olgun Çelik,Orçun Çiftci,Murat Muratoğlu,İbrahim Haldun Müderrsioğlu

Online publish date: 14 October 2020

DOI: 10.22514/sv.2020.16.0076

Abstract ( 97 ) PDF (226.38 kB) ( 16 )

Open Access

Performing General Surgery Emergencies Safely during COVID-19 Outbreak

Ozlem Zeliha Sert,Sevcan Alkan Kayaoglu

Online publish date: 14 October 2020

DOI: 10.22514/sv.2020.16.0077

Abstract ( 71 ) PDF (190.79 kB) ( 4 )

Open Access

Anesthetic Management of Patients Undergoing Renal Transplantation: A Review of A Two-year Experience

Burhan Dost,Muzeyyen Beldagli,Cengiz Kaya,Yasemin Burcu Ustun,Sezgin Bilgin,Ersin Koksal,Yakup Bostancı

Online publish date: 14 October 2020

DOI: 10.22514/sv.2020.16.0078

Abstract ( 117 ) PDF (192.28 kB) ( 16 )

Special Issues

Special issue title:

Advance in Acute Coronary Syndrome and Myocardial Infarction

Keywords: Myocardial infarction, Acute coronary syndrome, ST-elevation myocardial infarction, Non-ST elevation myocardial infarction, Unstable angina, Primary coronary intervention

Editor: Dr. Shou-Yen Chen

Submission deadline: 31 May 2021

Special issue title:

Pathophysiology of Sepsis

Keywords: Sepsis, Hyperinflammatory response, Dysregulated coagulation, Cellular dysfunction, Immunosuppression, Metabolism, Organ dysfunction, Immunocompromise

Editor: Dr. Susan F. Fitzpatrick

Submission deadline: 31 August 2021

Special issue title:

New Insights in Acute Respiratory Distress Syndrome

Keywords: Acute respiratory distress syndrome (ARDS), Intensive care, Heterogeneity, Personalized interventions, Cointerventions, Incorporating comorbidities, Clinical trial

Editor: Prof. Dr. Antonio Artigas

Submission deadline: 01 August 2021

Special issue title:

Next-generation Metabolomics in Critical Care Medicine

Keywords: Omics, Metabolomics, Lipidomics, Critical Care Medicine, Biomarkers, Prognosis

Editor: Dr. Kefeng Li,Dr. Jing Wang

Submission deadline: 31 August 2021

Special issue title:

Covid-19 ARDS: a multidisciplinary challenge

Keywords: SARS-CoV-2, COVID-19, COVID-19-induced acute respiratory distress syndrome, Pathophysiology, Diagnostic tools, Imaging Therapeutic perspectives, Psychological impact, Sequelae of COVID-19, Pain

Editor: Dr Marco Cascella,Dr. Alessandro Vittori

Submission deadline: 01 May 2021

Special issue title:

Emergency Medicine and Ethics

Keywords: Emergency medicine, Prehospital emergency medicine, ethics, triage, refusal of treatment, Withholding or withdrawal of CPR, Informed consent, Justice, Ethical principles, Values and conflicts

Editor: Asst. Prof. Dr. Hasan Erbay

Submission deadline: 31 July 2021

Special issue title:

Managing Coma in Critically Ill Patients: Clinical Neurophysiology

Keywords: Conscious awareness, Electro-physiologic testing, Neurophysiology,Acutely brain injury, prognostic, Neuro-critical care, Diagnosing, Coma

Editor: Assit. Prof. Dr. Francesco Lolli

Submission deadline: 30 June 2021

Special issue title:

Management of Severe Burns in the Context of COVID-19 Pandemic

Keywords: Burn injury, Critical care, Intensive management, SARS-CoV-2, COVID-19, Pandemic, Healthcare system, Response actions, Clinical service management, Clinical service reconfiguration

Editor: Dr. Ilaria Tocco-Tussardi

Submission deadline: 30 June 2021

Latest tweets


SepsEast and COVID-19: Time to Make a Difference #COVID-19 #SepsEast

24 July 2020

To Be a Reviewer

If you would like to volunteer to review a manuscript for Signa Vitae journal, please click “Review for SV” below to register at our submission website or log in our Online Peer Review system. Your name, contact details, and expertise will be automatically added to our database of reviewers.

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Join Editorial Board

You are welcome to join our editorial board. Our journal produces and issues editorial board certificates for editorial board members, and the journal website will display the names and personal websites of editorial board members to help enhance their scientific influence. Members of the editorial committee are entitled to 2 free publications (both editorial member’s or recommended paper) per year, and other articles over 2 can enjoy 30% discount of publishing fee.

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Prof Alan Šustić ,Editor-in-Chief

Alan Šustić, MD PhD, is a specialist in anesthesiology, emergency and intensive care medicine, and he is a member of numerous European and world societies and associations in the field of emergency and intensive care medicine. He is the Head of the Department of Anesthesiology, Reanimatology, Emergency and Intensive Care Medicine, Faculty of Medicine, University of Rijeka, Croatia, also he is a former Dean of Faculty of Medicine and he is a current Dean of Faculty of Health Studies, University of Rijeka, Croatia. A special field of his scientific interest is the application of ultrasound in emergency and intensive care medicine.