Aims and scope

The aim of Signa Vitae (SV) is to be an unbiased and permanent forum for clinical anesthesia, intensive care, emergency and pain medicine. It serves professionals dedicated to all these relevant fields, as a tool for easier and more effective experiences and science sharing, with the ultimate goal to improve patients’ outcome. The scope of Signa Vitae is broad. It encompasses all aspects of clinical practice and fundamental research at the basis of anesthesia, intensive care, emergency and pain medicine, both in children and adults. It will better inform and educate the global scientific and medical community on the advancements in the fields at the basis of survival and a better quality of life, as stated in the appealing Latin version of its name: "Signs of life". 


Open Access Special Issue

From little adults to pediatric patients: quality improvement in pediatric anesthesia

Nicola G. Clausen,Tom Giedsing Hansen

DOI: 10.22514/sv.2021.088

Abstract ( 757 ) PDF (163.86 kB) ( 231 )

Open Access Special Issue

Hydrocephalus after aneurysmal subarachnoid hemorrhage: Epidemiology, Pathogenesis, Diagnosis, and Management

Yu-Chang Wang,Xiao-Qiang Wang,Chang-Wu Tan,Chuan-Sen Wang,Zhi Tang,Zhi-Ping Zhang,Jing-Ping Liu,Ge-Lei Xiao

DOI: 10.22514/sv.2021.021

Abstract ( 1026 ) PDF (740.01 kB) ( 238 )

Open Access Special Issue

Applications of capnography in airway management outside the operating room

Chia-Hsiang Huang,Ko-Hsin Wei

DOI: 10.22514/sv.2021.061

Abstract ( 459 ) PDF (864.18 kB) ( 197 )

Open Access Special Issue

NGAL in trans-catheter aortic valve implantation on and off RenalGuard

Sapir Sadon,Yaron Arbel,Ariel Banai,Keren-Lee Rozenfeld,Phillipe Taieb,Aviram Hochstadt,Yacov Shacham,Shmuel Banai,Ariel Finkelstein,Ilan Merdler

DOI: 10.22514/sv.2021.048

Abstract ( 491 ) PDF (187.56 kB) ( 172 )

Open Access

Safety and effectiveness of deep sedation in pediatric patients undergoing flexible fibroscopy in spontaneous breathing

Federica Tosi,Giorgio Conti,Rossano Festa,Aldo Mancino,Marco Rossi,Antonio Chiaretti,Lavinia Capossela,Antonio Gatto

DOI: 10.22514/sv.2021.049

Abstract ( 770 ) PDF (472.33 kB) ( 175 )

Open Access Special Issue

Fear of the COVID-19 and medical liability. Insights from a series of 130 consecutives medico-legal claims evaluated in a single institution during SARS-CoV-2-related pandemic

Matteo Nioi,Pietro Emanuele Napoli,Gabriele Finco,Roberto Demontis,Maurizio Fossarello,Ernesto d'Aloja

DOI: 10.22514/sv.2021.098

Abstract ( 574 ) PDF (1.15 MB) ( 197 )

Open Access Special Issue

Initial capnography values and resuscitation outcomes of patients assisted by basic life support units in first instance; descriptive prospective study

Francisco José Cereceda-Sánchez,Jaume Ponce-Taylor,Pedro Montero-París,Iñaki Unzaga-Ercilla,Natalia Martinez-Cuellar,Jesús Molina-Mula

DOI: 10.22514/sv.2021.099

Abstract ( 451 ) PDF (188.44 kB) ( 170 )

Open Access

Protective effect of dapagliflozin on colistin-induced renal toxicity

Ejder Saylav Bora,Mumin Alper Erdogan,Ayfer Meral,Zeynep Karakaya,Oytun Erbas

DOI: 10.22514/sv.2021.020

Abstract ( 586 ) PDF (1.01 MB) ( 162 )

Open Access Special Issue

Association of patient-to-emergency department staff ratio with the incidence of cardiac arrest: A retrospective cohort study

Li-Heng Tsai,Wei-Che Chien,Chen-Bin Chen,Shang-Li Tsai,Chung-Hsien Chaou,Yi-Ming Weng,Chip-Jin Ng,Chen-June Seak,Shou-Yen Chen,Chien-Hsiung Huang,Shao-Yu Fang,Chi-Chun Lin,Cheng-Yu Chien

DOI: 10.22514/sv.2021.029

Abstract ( 670 ) PDF (484.81 kB) ( 160 )

Open Access Special Issue

Endovascular treatment for acute basilar artery occlusion: descriptive analysis of the experience in a comprehensive stroke centre

Ignacio Saldaña-Inda,Herbert Tejada-Meza,Alberto Sainz-Pardo,Cristina Moreno-Loscertales,Javier Marta-Moreno

DOI: 10.22514/sv.2021.038

Abstract ( 490 ) PDF (646.43 kB) ( 171 )

Open Access Special Issue

Comparison of the effects of desflurane and sevoflurane on emergence characteristics in pediatric patients premedicated with ketamine

Hyojoong Kim,Ki Hwa Lee,Yei Heum Park,Soo Jung Lee,Se Hun Kim,Sang Eun Lee,Yong Han Kim,Yu Kyung Jeon

DOI: 10.22514/sv.2021.045

Abstract ( 512 ) PDF (726.75 kB) ( 171 )

Open Access

Effectiveness of chest compressions after a short training method: a pilot study with future lifeguards

Brais Ruibal-Lista,Katlyn Marcela Hernández-Gil,José Palacios-Aguilar,Sergio López-García

DOI: 10.22514/sv.2021.074

Abstract ( 423 ) PDF (320.24 kB) ( 170 )

Open Access

miR-20a attenuates acute lung injury in septic rats via targeting TLR4

Shuping Li,Yang Sun,Xingming Tang,Li Wang,Xiaoyuan Cheng

DOI: 10.22514/sv.2021.097

Abstract ( 368 ) PDF (1.6 MB) ( 165 )

Open Access

Moral distress among health care workers in the intensive care unit; a systematic review and meta-analysis

Rakan M. AlQahtani,Abdalrhman Al Saadon,Mohammed Ibrahim Alarifi,Ruaim Muaygil,Yasmeen Khalaf Maan Altaymani,Mohamed Abdelwahab Mohamed Elsaid,Fahad Alsohime,Mohamad-Hani Temsah,Khaldoon Aljerian

DOI: 10.22514/sv.2021.101

Abstract ( 742 ) PDF (2.48 MB) ( 136 )

Open Access Special Issue

Children undergoing anaesthesia: what are the rights of the child?

Kristian Noerholm Jensen,Tom Giedsing Hansen

DOI: 10.22514/sv.2021.059

Abstract ( 368 ) PDF (221.96 kB) ( 154 )

Open Access

Accidental self-injection of intravenous epinephrine by healthcare personnel

Hyunseung Koh,Duk Ho Kim,Jinseong Kim,Heebum Yang

DOI: 10.22514/sv.2021.033

Abstract ( 656 ) PDF (726.71 kB) ( 209 )

Published Ahead of Print

Open Access Special Issue

Acquired brain injuries: neurophysiology in early prognosis and rehabilitation pathway

Maenia Scarpino,Giovanni Lanzo,Bahia Hakiki,Raisa Sterpu,Antonio Maiorelli,Francesca Cecchi,Francesco Lolli,Antonello Grippo

Online publish date: 30 July 2021

DOI: 10.22514/sv.2021.132

Abstract ( 196 ) PDF (1.68 MB) ( 103 )

Open Access

A statistical analysis for the epidemiological surveillance of COVID-19 in Chile

Nixon Jerez-Lillo,Bernardo Lagos Álvarez,Joel Muñoz Gutiérrez,Jorge I. Figueroa-Zúñiga,Víctor Leiva

Online publish date: 27 July 2021

DOI: 10.22514/sv.2021.130

Abstract ( 302 ) PDF (1 MB) ( 156 )

Open Access

Airway management in vascular central airway obstruction: a literature review

Shih-Yi Lee,Chuan-Lei Chao,Sho-Ting Hung,Hwee-Kheng Lim,Hui-Chun Ku

Online publish date: 27 July 2021

DOI: 10.22514/sv.2021.131

Abstract ( 211 ) PDF (603.25 kB) ( 160 )

Open Access

Effect of age on the interaction between heart rate and mortality in prehospital trauma care

Ki Hong Kim,Kyoung Jun Song,Sang Do Shin,Young Sun Ro,Ki Jeong Hong,Joo Jeong,Jeong Ho Park

Online publish date: 14 July 2021

DOI: 10.22514/sv.2021.126

Abstract ( 294 ) PDF (362.91 kB) ( 161 )

Open Access

Quality of life and psychological assessment in patients with Fibromyalgia Syndrome during COVID-19 pandemic in Italy: prospective observational study

Vittorio Schweiger,Erica Secchettin,Giovanni Perini,Alvise Martini,Katia Donadello,Leonardo Gottin,Giovanna Del Balzo,Giustino Varrassi,Enrico Polati

Online publish date: 14 July 2021

DOI: 10.22514/sv.2021.127

Abstract ( 285 ) PDF (185.01 kB) ( 169 )

Special Issues

Special issue title:

Neurocritical care in pandemic and beyond

Keywords: Neurocritical Care, Stroke, Neurotrauma

Editor: Luis Rafael Moscote- Salazar, MD ,Tariq Janjua, MD

Submission deadline: 01 December 2022

Special issue title:

Medical Simulation - success in education, future of science

Keywords: medical simulation, emergency medicine, medical education

Editor: Tomasz Kłosiewicz, MD, MSc,Mateusz Puślecki, PhD

Submission deadline: 31 December 2022

Special issue title:

A patient in a life-threatening condition - challenges and new solutions during the COVID-19 pandemic

Keywords: COVID-19, life-threatening conditions, patient, psychophysical factors, education, simulation, virtual reality

Editor: Paweł Więch, RN, CEN, PhD, DSc

Submission deadline: 30 April 2022

Special issue title:

Fractures in elderly – the ongoing pandemic

Keywords: elderly patients, fragility fractures, mobility, osteosynthesis, joints replacement, periprosthetic fractures, multidisciplinary approach

Editor: Dr. Anze Kristan

Submission deadline: 30 April 2022

Special issue title:

Opioid Sparing Modalities in Perioperative and Critical Care Patients: opioids sparing analgesia pain perioperative

Keywords: Opioid misuse, Prescription opioids, Postsurgical pain, Perioperative strategies, Critical care

Editor: Dr. Michael O’Neil, Pharm.D.

Submission deadline: 28 March 2022

Special issue title:

21st Panhellenic Congress on Regional Anaesthesia, Pain Management and Palliative Care

Keywords: Regional Anaesthesia, Pain Management, Palliative Care, PARH.SY.A., ESRA HELLAS, the A’ Anaesthesiology Department, Faculty of Medicine, University of Athens

Editor: Dr. Ioanna Siafaka, MD, PhD,Dr. Maria Kokolaki, MD, PhD,Dr. Athina Vadalouca, MD, PhD, FIPP,Dr. Evmorfia Stavropoulou, MD, PhD, EDRA,Dr. Eleni Moka, MD, PhD, MSc, EDRA

Submission deadline: 27 May 2022

Special issue title:

Visceral Pain in Intensive Care and Emergency Medicine

Keywords: Internal organs; Referred pain; Visceral pain

Editor: Dr. Yu-Jang Su, MD

Submission deadline: 28 February 2022

Special issue title:

Cardiopulmonary emergencies in the COVID-19 era: What is on the horizon?

Keywords: COVID-19, Cardiopulmonary diseases, emergency medicine, intensive care, healthcare system, diagnosis, treatment

Editor: Prof. Ozgur KARCIOGLU, MD, FEMAT

Submission deadline: 19 March 2022

Special issue title:

The Impact of COVID-19 Pandemic on Critical Healthcare System

Keywords: COVID-19, emergency medicine, intensive care, healthcare system

Editor: Prof. Yao-Chin Wang, MD, PhD

Submission deadline: 31 December 2021

Special issue title:

Selected papers from Korean Association of Cardiopulmonary Resuscitation in 2021

Keywords: Cardiac arrest, Resuscitation, cardiopulmonary resuscitation, guidelines, outcome

Editor: Prof. Won Young Kim, MD, PhD

Submission deadline: 01 June 2022

Featured Article

A Novel Objective Approach Towards Physicians' Knowledge and Practice Patterns to Optimize Central Venous Catheter Placement: A Cross-sectional Study. DOI: 10.22514/sv.2020.16.0052

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You are welcome to join our editorial board. Our journal produces and issues editorial board certificates for editorial board members, and the journal website will display the names and personal websites of editorial board members to help enhance their scientific influence. Members of the editorial committee are entitled to 2 free publications (both editorial member’s or recommended paper) per year, and other articles over 2 can enjoy 30% discount of publishing fee.

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  2020 has been a very special year, full of events, frequently strange and newly shaped events. As always, humanity has tried to learn from them, searching (and frequently finding) the best solution to the problems. “Work is the best gymnasium where to exercise the intelligence”. This was an excellent definition for “work”. 2020 has obliged anyone to work with new obstacles and to find always new solutions, exercising the intelligence. It is also possible to say that 2020 has provided mankind a fantastic opportunity to express at maximum level its potentialities.

  Between others, I was kindly invited to becoming Editor in Chief of this important journal. Signa Vitae has a nice story, but its aim is to increase its impact in the scientific community. The scientific community deriving from the initial “Anesthesiology”, as it was in the first decades of the twentieth century, in the course of the years has expanded enormously. Now it still covers “Anesthesiology”, but it also covers Emergency, Intensive Cares, Supportive Medicine, and last but not least Pain Medicine. In other terms, the name of the journal, Signa Vitae (“Signs of Life”, with a nuance of Latin classic culture), is extremely appropriate.

  Considering my personal story, the diffusion of Signa Vitae in the field of Pain Medicine will be a natural consequence. The new challenge will definitely be to establish a strong Editorial Board, with Section Editors, and attract high quality papers from the other branch of the medical specialty. For this, the journal counts on the support of most of the Members of the Editorial Board whose story is deeply rooted in Emergency and Intensive Cares.

  The programs for 2021 are incredibly challenging and stimulating. It will be a year of hard work and growth, and the Signa Vitae family is ready to obtain the best possible. I want to take this opportunity to thank the publisher and the Signa Vitae team for their trust in my enthusiasm, inviting me as Editor-in-Chief of a nice and promising journal. Ad majora to all of them and especially to the Authors that will be confident on the potentialities of this journal. Let’s work together for it.

Giustino Varrassi, MD, PhD

Paolo Procacci Foundation, Via Tacito 7, 00193 Roma, Italy