Investigating the effectiveness and safety of radiofrequency damage of the lumbar sympathetic ganglia on alcoholic peripheral neuropathy pain

This study examines the effectiveness and safety of using radiofrequency damage to treat pain caused by alcoholic peripheral neuropathy by targeting the lumbar sympathetic ganglia. Alcoholic peripheral neuropathy is a form of peripheral neuropathy that occurs as a result of prolonged alcohol consumption. Radiofrequency damage of the lumbar sympathetic ganglia allows precise targeting and destruction of the lumbar sympathetic ganglia, frequently alleviating vascular or sympathetic reflex pain in the lower back and legs. A retrospective analysis was conducted on the clinical data of 100 patients who received treatment at our hospital from March 2021 to March 2023. Based on the treatment method, the patients were categorized into two groups: an experimental group (50 cases) and a control group (50 cases). The control group received conventional treatment, while the experimental group underwent radiofrequency damage to the lumbar sympathetic ganglia in addition to conventional treatment. The effectiveness and safety of the two treatment methodologies were evaluated and compared. After one month and three months of treatment, the experimental group demonstrated significantly lower pain scores and decreased levels of tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), and interleukin-8 (IL-8) as compared to the control group (p < 0.001). In addition, the experimental group showed faster motor nerve conduction velocity (MNCV) and sensory nerve conduction velocity (SNCV) in the median nerve and common peroneal nerve compared to the control group (p < 0.05). There was no statistically significant difference in the occurrence of complications between the two groups (p > 0.05). Radiofrequency damage of the lumbar sympathetic ganglion for treating pain caused by alcoholic peripheral neuropathy effectively inhibits inflammatory responses, significantly alleviates patient pain, improves nerve conduction function, and is safe, making it a promising clinical treatment.

Radiofrequency damage; Lumbar sympathetic ganglia; Alcoholic peripheral neuropathy

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