Article Data

  • Views 1821
  • Dowloads 119

Original Research

Open Access

Severe mental illness and non-specific abdominal pain in the emergency department: a multi-institutional database study

  • Wei-Che Chien1,2
  • Hao-Wei Kou3
  • Kai-Hsiang Wu4
  • Shi-Ying Gao1
  • Chip-Jin Ng1,5
  • Yu-Yung Hung6
  • Chao-Wei Lee3,5
  • Chih-Huang Li1
  • Shang-Kai Hung1,2,*,

1Department of Emergency Medicine, Linkou Chang Gung Memorial Hospital, 333 Taoyuan, Taiwan

2Department of Emergency Medicine, Keelung Chang Gung Memorial Hospital, 204 Keelung, Taiwan

3Division of General Surgery, Department of Surgery, Linkou Chang Gung Memorial Hospital, 333 Taoyuan, Taiwan

4Department of Emergency Medicine, Chiayi Chang Gung Memorial Hospital, 613 Chiayi, Taiwan

5College of Medicine, Chang Gung University, 333 Taoyuan, Taiwan

6Department of Psychiatry, Taipei Veterans General Hospital Taitung Branch, 950 Taitung, Taiwan

DOI: 10.22514/sv.2024.097 Vol.20,Issue 8,August 2024 pp.40-47

Submitted: 23 December 2023 Accepted: 27 February 2024

Published: 08 August 2024

*Corresponding Author(s): Shang-Kai Hung E-mail: mm200411800@cgmh.org.tw

Abstract

Abdominal pain frequently leads to emergency department (ED) visits, with non-specific abdominal pain (NSAP) being a common diagnosis. Patients with severe mental illness (SMI) face higher risks due to atypical disease presentations and elevated comorbidity rates. Studies show that patients with both SMI and NSAP have increased ED revisit rates and delayed diagnoses. This study examines ED management, unscheduled ED revisit rates, and short-term adverse outcomes in patients with both SMI and NSAP using data from the Chang Gung Research Database from 01 January 2007, to 31 December 2017. Diagnoses were confirmed through the International Classification of Diseases (ICD) codes and medical records, with a 1:3 matching ratio for the non-SMI group using a Greedy algorithm. The outcomes assessed were ED management, 72-hour unscheduled ED revisits, and 7-day adverse events. From seven hospitals, 233,671 patients were initially included over 11 years; 98,722 were excluded, leaving 134,949 for analysis. The SMI group showed higher comorbidity rates, more frequent 72-hour unscheduled ED revisits, and greater use of analgesics but were less likely to receive laboratory tests or CT scans. Non-SMI patients were more likely to be admitted to the hospital and receive invasive procedures within 7 days after index discharge. There were no significant differences in intensive care unit (ICU) admissions, abdominal surgery, or in-hospital mortality between the groups. This study indicates that while patients with SMI and NSAP have higher 72-hour ED revisit rates, they do not experience higher short-term adverse outcomes. Although NSAP is generally safe for all patients, the higher unscheduled revisit rate highlights the need for tailored healthcare interventions to reduce health disparities in this vulnerable group. Future efforts should focus on strategies to improve healthcare for individuals with SMI and NSAP.


Keywords

Severe mental illness; Non-specific abdominal pain; Emergency department; Unscheduled emergency department revisit


Cite and Share

Wei-Che Chien,Hao-Wei Kou,Kai-Hsiang Wu,Shi-Ying Gao,Chip-Jin Ng,Yu-Yung Hung,Chao-Wei Lee,Chih-Huang Li,Shang-Kai Hung. Severe mental illness and non-specific abdominal pain in the emergency department: a multi-institutional database study. Signa Vitae. 2024. 20(8);40-47.

References

[1] Cervellin G, Mora R, Ticinesi A, Meschi T, Comelli I, Catena F, et al. Epidemiology and outcomes of acute abdominal pain in a large urban emergency department: retrospective analysis of 5340 cases. Annals of Translational Medicine. 2016; 4: 362.

[2] Arvig MD, Mogensen CB, Skjøt-Arkil H, Johansen IS, Rosenvinge FS, Lassen AT. Chief complaints, underlying diagnoses, and mortality in adult, non-trauma emergency department visits: a population-based, multicenter cohort study. The Western Journal of Emergency Medicine. 2022; 23: 855–863.

[3] Fagerström A, Paajanen P, Saarelainen H, Ahonen-Siirtola M, Ukkonen M, Miettinen P, et al. Non-specific abdominal pain remains as the most common reason for acute abdomen: 26-year retrospective audit in one emergency unit. Scandinavian Journal of Gastroenterology. 2017; 52: 1072–1077.

[4] Yau FF, Yang Y, Cheng CY, Li CJ, Wang SH, Chiu IM. Risk factors for early return visits to the emergency department in patients presenting with nonspecific abdominal pain and the use of computed tomography scan. Healthcare. 2021; 9: 1470.

[5] Lukens TW, Emerman C, Effron D. The natural history and clinical findings in undifferentiated abdominal pain. Annals of Emergency Medicine. 1993; 22: 690–696.

[6] Karcioglu O. Nonspecific abdominal pain: do I have to allocate a specific diagnosis for every patient? Signa Vitae. 2022; 18: 1–4.

[7] Zabeen S, Lawn S, Venning A, Fairweather K. Why do people with severe mental illness have poor cardiovascular health? The need for implementing a recovery-based self-management approach. International Journal of Environmental Research and Public Health. 2021;18: 12556.

[8] Luciano M, Pompili M, Sartorius N, Fiorillo A. Editorial: mortality of people with severe mental illness: causes and ways of its reduction. Frontiers in Psychiatry. 2022; 13: 1009772.

[9] Oliveira J. E Silva L, Prakken SD, Meltzer AC, Broder JS, Gerberi DJ, Upadhye S, et al. Depression and anxiety screening in emergency department patients with recurrent abdominal pain: an evidence synthesis for a clinical practice guideline. Academic Emergency Medicine. 2022; 29: 615–629.

[10] Meltzer AC, Bregman B, Blanchard J. Depression is associated with repeat emergency department visits in patients with non-specific abdominal pain. Western Journal of Emergency Medicine. 2014; 15: 325–328.

[11] Retamero C, Paglia C. When patients do not hurt: silent acute abdomen in a patient with schizophrenia. General Hospital Psychiatry. 2012; 34: 210.e9–210.e11.

[12] Kallur A, Yoo E, Bien-Aime F, Ammar H. Diagnostic overshadowing and pain insensitivity in a schizophrenic patient with perforated duodenal ulcer. Cureus. 2022; 14: e21800.

[13] Katz E, Kluger Y, Rabinovici R, Stein D, Gimmon Z. Acute surgical abdominal disease in chronic schizophrenic patients: a unique clinical problem. Israel Medical Association Journal. 1990; 26: 275–277.

[14] Tsai M, Lin M, Lee C, Yang Y, Chen W, Chang G, et al. Chang gung research database: a multi-institutional database consisting of original medical records. Biomedical Journal. 2017; 40: 263–269.

[15] Shao S, Chan Y, Kao Yang Y, Lin S, Hung M, Chien R, et al. The Chang gung research database—a multi-institutional electronic medical records database for real-world epidemiological studies in Taiwan. Pharmacoepidemiology and Drug Safety. 2019; 28: 593–600.

[16] Huang Y, Chen Y, Chang S, Kuo C, Chen M. Discharge status validation of the Chang gung research database in Taiwan. Biomedical Journal. 2022; 45: 907–913.

[17] Huang Y, Gou R, Diao Y, Yin Q, Fan W, Liang Y, et al. Charlson comorbidity index helps predict the risk of mortality for patients with type 2 diabetic nephropathy. Journal of Zhejiang University Science B. 2014; 15: 58–66.

[18] Charlson ME, Carrozzino D, Guidi J, Patierno C. Charlson comorbidity index: a critical review of clinimetric properties. Psychotherapy and Psychosomatics. 2022; 91: 8–35.

[19] Jungnickel D. The greedy algorithm. Graphs, Networks and Algorithms. 1999; 5: 129–153.

[20] Skrivankova VW, Richmond RC, Woolf BAR, Yarmolinsky J, Davies NM, Swanson SA, et al. Strengthening the reporting of observational studies in epidemiology using mendelian randomization. JAMA. 2021; 326: 1614.

[21] Al-Mashat H, Lindskou TA, Møller JM, Ludwig M, Christensen EF, Søvsø MB. Assessed and discharged—diagnosis, mortality and revisits in short-term emergency department contacts. BMC Health Services Research. 2022; 22: 816.

[22] Hutchinson CL, Curtis K, McCloughen A, Qian S, Yu P, Fethney J. Identifying return visits to the emergency department: a multi-centre study. Australasian Emergency Care. 2021; 24: 34–42.

[23] Fikree A, Byrne P. Management of functional gastrointestinal disorders. Clinical Medicine. 2021; 21: 44–52.

[24] Wu JC. Psychological co-morbidity in functional gastrointestinal disorders: epidemiology, mechanisms and management. Journal of Neurogastroenterology and Motility. 2012; 18: 13–18.

[25] North CS. Relationship of functional gastrointestinal disorders and psychiatric disorders: implications for treatment. World Journal of Gastroenterology. 2007; 13: 2020.

[26] Ålander T, Svärdsudd K, Johansson S, Agréus L. Psychological illness is commonly associated with functional gastrointestinal disorders and is important to consider during patient consultation: a population-based study. BMC Medicine. 2005; 3: 8.

[27] Drossman DA, Hasler WL. Rome IV—functional GI disorders: disorders of gut-brain interaction. Gastroenterology. 2016; 150: 1257–1261.

[28] Niedzwiecki MJ, Sharma PJ, Kanzaria HK, McConville S, Hsia RY. Factors associated with emergency department use by patients with and without mental health diagnoses. JAMA Network Open. 2018; 1: e183528.

[29] Fang A, Hersh M, Birgisson N, Saynina O, Wang NE. “Could we have predicted this?” the association of a future mental health need in young people with a non-specific complaint and frequent emergency department visits. Journal of the American College of Emergency Physicians Open. 2021; 2: e12556.

[30] Saaristo L, Ukkonen MT, Laukkarinen JM, Pauniaho SK. The rate of short-term revisits after diagnosis of non-specific abdominal pain is similar for surgeons and emergency physicians-results from a single tertiary hospital emergency department. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. 2020; 28: 63.

[31] Shou-Hsia C. The effect of universal health insurance on health care utilization in Taiwan. JAMA. 1997; 278: 89.

[32] Sabbatini AK, Kocher KE, Basu A, Hsia RY. In-hospital outcomes and costs among patients hospitalized during a return visit to the emergency department. JAMA. 2016; 315: 663.

[33] Tsai CL, Ling DA, Lu TC, Lin JC, Huang CH, Fang CC. Inpatient outcomes following a return visit to the emergency department: a nationwide cohort study. The Western Journal of Emergency Medicine. 2021; 22: 1124–1130.

[34] Guo DY, Chen KH, Chen IC, Lu KY, Lin YC, Hsiao KY. The association between emergency department revisit and elderly patients. Journal of Acute Medicine. 2020; 10:20–26.

[35] Hsu CC, Chu CJ, Lin CH, Huang CH, Ng CJ, Lin GY, et al. A machine learning model for predicting unscheduled 72 h return visits to the emergency department by patients with abdominal pain. Diagnostics. 2021; 12: 82.

[36] Hung S, Kou H, Wu K, Chen S, Li C, Lee C, et al. Does medical disparity exist while treating severe mental illness patients with acute appendicitis in emergency departments? A real-world database study. BMC Psychiatry. 2022; 22: 488.

[37] Wang LH, Lee HL, Lin CC, Lan CJ, Huang PT, Han CY. Factors associated with return visits by elders within 72 hours of discharge from the emergency department. Healthcare. 2023; 11: 1726.

[38] Fruhan S, Bills CB. Association of a callback program with emergency department revisit rates among patients seeking emergency care. JAMA Network Open. 2022; 5: e2213154.

[39] Moss JE, Houghton LM, Flower CL, Moss DL, Nielsen DA, Taylor DM. A multidisciplinary care coordination team improves emergency department discharge planning practice. Medical Journal of Australia. 2002; 177: 427–439.

[40] Biese K, Lash TA, Kennedy M. Emergency department care transition programs—value-based care interventions that need system-level support. JAMA Network Open. 2022; 5: e2213160.

[41] Gettel CJ, Hastings SN, Biese KJ, Goldberg EM. Emergency department-to-community transitions of care: best practices for the older adult population. Clinics in Geriatric Medicine. 2023; 39: 659–672.


Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,200 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Chemical Abstracts Service Source Index The CAS Source Index (CASSI) Search Tool is an online resource that can quickly identify or confirm journal titles and abbreviations for publications indexed by CAS since 1907, including serial and non-serial scientific and technical publications.

Index Copernicus The Index Copernicus International (ICI) Journals database’s is an international indexation database of scientific journals. It covered international scientific journals which divided into general information, contents of individual issues, detailed bibliography (references) sections for every publication, as well as full texts of publications in the form of attached files (optional). For now, there are more than 58,000 scientific journals registered at ICI.

Geneva Foundation for Medical Education and Research The Geneva Foundation for Medical Education and Research (GFMER) is a non-profit organization established in 2002 and it works in close collaboration with the World Health Organization (WHO). The overall objectives of the Foundation are to promote and develop health education and research programs.

Scopus: CiteScore 1.3 (2023) Scopus is Elsevier's abstract and citation database launched in 2004. Scopus covers nearly 36,377 titles (22,794 active titles and 13,583 Inactive titles) from approximately 11,678 publishers, of which 34,346 are peer-reviewed journals in top-level subject fields: life sciences, social sciences, physical sciences and health sciences.

Embase Embase (often styled EMBASE for Excerpta Medica dataBASE), produced by Elsevier, is a biomedical and pharmacological database of published literature designed to support information managers and pharmacovigilance in complying with the regulatory requirements of a licensed drug.

Submission Turnaround Time

Conferences

Top