Article Data

  • Views 450
  • Dowloads 152

Meeting Abstracts

Open Access

Shpenopalatine ganglion block using the Tx360 nasal applicator for the treatment of trigeminal neuralgia: A pilot study

  • Athanasia Tsaroucha1
  • Christina Orfanou1
  • Aikaterini Melemeni1
  • Nikolaos Fyrfiris2
  • Kassiani Theodoraki1

11st Department of Anesthesiology, Aretaieio Hospital, National and Kapodistrian University of Athens, Athens, Greece

2General Anti-cancer – Oncology Hospital of Athens ‘Agios Savvas’, Athens, Greece

DOI: 10.22514/sv.2021.160 Vol.17,Issue S1,September 2021 pp.13-13

Submitted: 26 August 2021 Accepted: 06 September 2021

Published: 15 September 2021

*Corresponding Author(s): Christina Orfanou E-mail: chrisorf@hotmail.com

Abstract

Background: Sphenopalatine ganglion (SPG) is located within the pterygopalatine fossa, being the only ganglion outside the cranial cavity. Trigeminal neuralgia (TGN) is currently considered as an indication for SPG block, especially in medication-resistant cases. The aim of this observational study is to assess the effectiveness of the SPG block for the treatment of trigeminal neuralgia, using a noninvasive transnasal approach, by delivering local anesthetic with the alternative device Tx360 nasal applicator.

Methods: This study concerns patients suffering drug-resistant TGN. In addition to their medication, these patients received SPG block, using the Tx360 nasal applicator in order to deliver 0.3 mL of xylocaine 2%, bilaterally, once a week, for 8 weeks. Eight patients presented with either classical or atypical, V2 (maxillary branch) or V3 (mandibular branch) TGN, partly or completely drug-resistant, having VAS = 8–9, under drug treatment, with no clinical improvement.

Results: All patients reported significant pain relief, VAS = 5–6 (3 patients since the first application) and decrease of daily pain episodes. Specifically, after completing therapy, 6 patients were completely symptom-free, 1 reported significant clinical improvement regarding pain intensity and number of pain episodes and 1 patient reported no improvement at any disease level. Favorable outcomes have lasted for up to 3 months for each case. No significant adverse events were noted to any patient.

Conclusions: Preliminary data extracted from this pilot study suggest that repetitive SPG block with the Tx360 nasal applicator may constitute an easy, rapid, safe and efficient treatment of trigeminal neuralgia. Further relative double-blind, randomized studies are required in order to draw solid conclusions.


Cite and Share

Athanasia Tsaroucha,Christina Orfanou,Aikaterini Melemeni,Nikolaos Fyrfiris,Kassiani Theodoraki. Shpenopalatine ganglion block using the Tx360 nasal applicator for the treatment of trigeminal neuralgia: A pilot study. Signa Vitae. 2021. 17(S1);13-13.

References

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,200 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Chemical Abstracts Service Source Index The CAS Source Index (CASSI) Search Tool is an online resource that can quickly identify or confirm journal titles and abbreviations for publications indexed by CAS since 1907, including serial and non-serial scientific and technical publications.

IndexCopernicus The Index Copernicus International (ICI) Journals database’s is an international indexation database of scientific journals. It covered international scientific journals which divided into general information, contents of individual issues, detailed bibliography (references) sections for every publication, as well as full texts of publications in the form of attached files (optional). For now, there are more than 58,000 scientific journals registered at ICI.

Geneva Foundation for Medical Education and Research The Geneva Foundation for Medical Education and Research (GFMER) is a non-profit organization established in 2002 and it works in close collaboration with the World Health Organization (WHO). The overall objectives of the Foundation are to promote and develop health education and research programs.

Scopus: CiteScore 0.5(2019) Scopus is Elsevier's abstract and citation database launched in 2004. Scopus covers nearly 36,377 titles (22,794 active titles and 13,583 Inactive titles) from approximately 11,678 publishers, of which 34,346 are peer-reviewed journals in top-level subject fields: life sciences, social sciences, physical sciences and health sciences.

Embase Embase (often styled EMBASE for Excerpta Medica dataBASE), produced by Elsevier, is a biomedical and pharmacological database of published literature designed to support information managers and pharmacovigilance in complying with the regulatory requirements of a licensed drug.

Submission Turnaround Time

Conferences

Top