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Original Research

Open Access Special Issue

Myocardial infarction with cardiogenic shock---the experience of a primary PCI centre from North-East Romania

  • Larisa Anghel1,2
  • Radu Sascău1,2
  • Cristian Stătescu1,2

1Internal Medicine Department, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, Romania

2Cardiology Department, Cardiovascular Diseases Institute “Prof. Dr. George I.M.Georgescu”, 700503 Iasi, Romania

DOI: 10.22514/sv.2021.070 Vol.17,Issue 5,September 2021 pp.64-70

Submitted: 25 February 2021 Accepted: 16 March 2021

Published: 08 September 2021

*Corresponding Author(s): Radu Sascău E-mail: radu.sascau@gmail.com

Abstract

Objectives: To evaluate the severity of acute myocardial infarction (AMI) complicated with cardiogenic shock (CS), by comparison with inferior and right ventricular AMI, which is also considered a severe form of myocardial infarction.

Methods: In an observational study, from 774 patients with STEMI hospitalized in our Cardiology Institute, over one year and a half, only 120 patients met the inclusion and exclusion criteria (60 patients with CS and 60 patients with right ventricular AMI). Data collected included age, sex, vital signs, oxygen saturation, respiratory rate, left ventricular ejection fraction, right ventricular dysfunction, complications during hospitalization and coronarography results.

Results: Patients with CS had a more severe systolic dysfunction (median ejection fraction 22.72 ± 12.30% vs. 41.93 ± 10.50%, P < 0.0001). Single-vessel disease was the most common in both groups, left anterior descending artery being the culprit artery in most patients with cardiogenic shock, 25% of them having residual lesions with a severity >75%. Using a multivariate analysis, we observed that for patients with CS, delayed coronary angiography evaluation, as well as the presence of severe triple-vessel disease, were associated with a higher risk of death. In-hospital mortality (53.33% vs. 8.33%, P < 0.0001) and ventricular arrhythmia were significantly higher in patients with CS (48.3% vs. 11.3%, P < 0.0001).

Conclusions: Our study suggests that patients with AMI and CS can be considered the most severe form of myocardial infarction and should, therefore, benefit of prompt and appropriate treatment, to improve the outcome.


Keywords

Cardiogenic shock; Ischaemic heart disease; Mortality; Right ventricular myocardial infarction


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Larisa Anghel,Radu Sascău,Cristian Stătescu. Myocardial infarction with cardiogenic shock---the experience of a primary PCI centre from North-East Romania. Signa Vitae. 2021. 17(5);64-70.

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