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Original Research

Open Access Special Issue

Establishment of a Linear Correlation Model of Central Venous Blood Oxygen Saturation and Lactate in Sepsis

  • Songchang Shi1
  • Xiaobin Pan1
  • Wei Lin2
  • Chao Wu1
  • Mei Ye1
  • Yingfeng Zhuang1
  • Jian Lin1
  • Xincai Wang1
  • Lihui Zhang1
  • Shujuan Zhang1
  • Hangwei Feng1
  • Long Huang1
  • Songjing Shi3
  • Xingsheng Lin1

1Department of Critical Care Medicine, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital South Branch, Fuzhou, 350001, P. R. China

2Department of Endocrinolog, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, FuZhou, 350001, P. R. China

3Department of Critical Care Medicine, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou ,350001, P. R. China

DOI: 10.22514/sv.2020.16.0064 Vol.17,Issue 1,January 2021 pp.101-105

Published: 08 January 2021

*Corresponding Author(s): Songjing Shi E-mail: songjingshifz@163.com
*Corresponding Author(s): Xingsheng Lin E-mail: xingshenglinfz@163.com

Abstract

Introduction: Studies have shown that there is a complex relationship between lactate and ScvO2. Methods: A retrospective study was carried out in 37 intensive care patients with sepsis or septic shock. The relationship between lactate and ScvO2 was explored with correlation analysis and simple linear modelling. Results: Lactate and ScvO2 were significantly correlated in patients with septic shock (r2 = 0.46, p = 0.001; y = -4.11x+ 82.62), but not in sepsis. y Significant correlation between these parameters was also found in the group of patients who went on to die (r2 = 0.67, p < 0.01; y = -3.70x + 78.61), but not in patients who survived. Conclusions: In sepsis, the correlation between ScvO2 and lactate is not constant over the sepsis course and may be dynamic. In the resuscitation of sepsis and/or septic shock, changes in ScvO2 requires further study.

Keywords

Central venous blood oxygen saturation, Lactate, Sepsis, Septic shock

Cite and Share

Songchang Shi,Xiaobin Pan,Wei Lin,Chao Wu,Mei Ye,Yingfeng Zhuang,Jian Lin,Xincai Wang,Lihui Zhang,Shujuan Zhang,Hangwei Feng,Long Huang,Songjing Shi,Xingsheng Lin. Establishment of a Linear Correlation Model of Central Venous Blood Oxygen Saturation and Lactate in Sepsis. Signa Vitae. 2021. 17(1);101-105.

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