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Original Research

Open Access

Sex Differences in Risk Factors Associated with Coronary Artery Disease: What Does Glycated Albumin Indicate?

  • Lin Sun1
  • Haitao Yuan1

1Department of Cardiovascular Disease, Shandong Provincial Hospital affiliated to Shandong University, Jinan, P.R. China

DOI: 10.22514/sv.2020.16.0018 Vol.16,Issue 1,June 2020 pp.137-145

Published: 30 June 2020

*Corresponding Author(s): Haitao Yuan E-mail:

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Objective: To investigate gender differences in risk factors associated with coronary artery disease (CAD), and to explore the association between glycated albumin (GA) and CAD. Method: We recruited 350 adult patients, collected their clinical information and divided them into CAD and non-CAD groups, based on angiography results. Results: Patients with CAD showed significantly higher age related GA, fasting blood glucose, serum creatinine (SCr) and Gensini score. Multivariate Logistic regression analysis identified gender, age, superoxide dismutase(SOD) and GA as independent factors in CAD patients (p < 0.05) and the mean GA level in females was higher than in males. Univariate linear regression analysis also showed that GA was not associated with male CAD patients. In females, SOD, low-density lipoprotein cholesterol (LDL-c), and GA were associated with a significant Gensini score (p < 0.05). Finally, GA was capable of classifying CAD in women (AUC > 0.767; p < 0.001). Conclusion: GA is positively correlated with the severity of coronary artery obstruction in female patients presenting with CAD.

Key words

Coronary artery disease, Angiography, Gensini score, Glycated albumin

Cite And Share

Lin Sun,Haitao Yuan. Sex Differences in Risk Factors Associated with Coronary Artery Disease: What Does Glycated Albumin Indicate?. Signa Vitae. 2020. 16(1);137-145.


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