Sympathetic hyperactivity syndrome following cerebral fat embolization
1,Department of Anesthesiology Divison of Critical Care Mayo Clinic
2Department of Neurology Division of Critical Care, Mayo Clinic
DOI: 10.22514/SV91.042014.10 Vol.9,Issue 1,April 2014 pp.53-56
Published: 30 April 2014
To date, there have been no reports of paroxysmal sympathetic hyperactivity syndrome (PSHS) associated with cerebral fat embolization. We describe the case of a young male who developed acute brain injury and acute hypoxemic respiratory failure secondary to significant fat embolization following a traumatic femur injury. Our patient demonstrated episodes of significant hypertension, tachycardia, fever and extensor posturing. Extensive evaluation lead to the diagnosis and appropri-ate treatment for PSHS. Ultimately, the patient went on to have a good neurologic recovery after a prolonged hospitalization. We will discuss PSHS diagnostic criteria, pathophysiology and treatment options. This diagnosis should be considered in all brain-injured patients with paroxysms of autonomic instability and abnormal movements.
acute brain injury, myoc-lonic encephalopathy, fat emboli-sm, autonomic nervous system diseases, adult respiratory distress syndrome,wound, injuries
JEFFREY B JENSEN,JAMES ONIGKEIT,SARA HOCKER. Sympathetic hyperactivity syndrome following cerebral fat embolization. Signa Vitae. 2014. 9(1);53-56.
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