Is NIRS monitoring well tolerated in term and preterm neonates?
1 Research Unit for Cerebral Development and Oximetry Research, Division of Neonatology, Department of Paediatrics, Medical University of Graz, Austria
2 Division of Neonatology, Department of Paediatrics, Medical University, Graz, Austria
3 Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Austria
4 Department of Paediatrics, University of Alberta, Edmonton, Canada
5 Neonatal Research Unit, Royal Alexandra Hospital, Edmonton, Canada
DOI: 10.22514/SV121.102016.12 Vol.12,Issue S1,October 2016 pp.70-73
Published: 10 October 2016
Background. Near infrared spectroscopy (NIRS) is a new, non-invasive monitoring method in neonates, which has now be-come part of routine monitoring in many neonatal intensive care units (NICU). New, additional, non-invasive technical moni-toring might have an influence on neonatal wellbeing.
Objectives. The aim of the present study was to evaluate the wellbeing of neonates during peripheral and cerebral NIRS mon-itoring and venous occlusions.
Methods. In the present study, secondary outcome parameters of prospective ob-servational studies with NIRS in term and preterm neonates were analysed. Heart rate (HR), arterial oxygen saturation (SpO2), respiratory rate (RR), mean arterial blood pressure (MABP), pain score and skin condition at four defined time points dur-ing NIRS measurements of regional tissue oxygenation were recorded and analysed. Results. Thirty-six term and preterm neo-nates were included (gestational age (GA) 36±1 week, 2779±930g birth weight). SpO2 and peripheral tissue oxygenation index (pTOI) increased and HR dropped while RR, mean MABP and pain scores re-mained unchanged during NIRS measure-ments. In eight infants, a mildly irritated area of skin was noted where the NIRS sen-sors had been attached.
Conclusion. Cerebral and peripheral NIRS monitoring and venous occlusions were painless and well tolerated by term and preterm neonates.
neonates, NIRS, vital signs
EVELYN ZIEHENBERGER,BERNDT URLESBERGER,CORINNA BINDER-HESCHL,BERNHARD SCHWABERGER,NICHOLAS MORRIS,NARIAE BAIK,ALEXANDER AVIAN,GERHARD PICHLER. Is NIRS monitoring well tolerated in term and preterm neonates?. Signa Vitae. 2016. 12(S1);70-73.
1. Jöbsis FF. Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters. Science 1977;198(4323):1264–7.
2. Nicklin SE, Hassan IA-A, Wickramasinghe YA, Spencer SA. The light still shines, but not that brightly? The current status of perinatal near infrared spectroscopy. Arch Dis Child Fetal Neonatal Ed 2003;88(4):F263-8.
3. Grossauer K, Pichler G, Schmoelzer G, Zotter H, Mueller W, Urlesberger B. Comparison of peripheral and cerebral tissue oxygena-tion index in neonates. Arch Dis Child Fetal Neonatal Ed 2009;94(2):F15. doi:10.1136/adc.2008.146654.
4. Pichler G, Heinzinger J, Kutschera J, Zotter H, Müller W, Urlesberger B. Forearm and Calf Tissue Oxygenation in Term Neonates Measured with Near-Infrared. J Physiol Sci 2007;57 (5):317–9. doi:10.2170/physiolsci.SC004407.
5. Pocivalnik M, Pichler G, Zotter H, Tax N, Müller W, Urlesberger B. Regional tissue oxygen saturation: comparability and reproduc-ibility of different devices. J Biomed Opt 2011;16(5):57004. doi:10.1117/1.3575647.
6. Catelin C, Tordjman S, Morin Vincen, Oger E, Sizun J. Clinical, Physiologic, and Biologic Impact of Environmental and Behavioral Interventions in Neonates During a Routine Nursing Procedure. J Pain 2005;6(12):791–7. doi:10.1016/j.jpain.2005.07.010
7. Gonsalves S, Mercer J. Physiological correlates of painful stimulation in preterm infants. Clin J Pain 1993;9(2):88–93.
8. Murdoch DR and Darlow BA. Handling during neonatal intensive care. Arch Dis Childhood 1984;59:957-61.
9. Büttner W, Finke W, Hilleke M, Reckert S, Vsianska L, Brambrink A. Development of an observational scale for assessment of post-operative pain in infants. Anästhesiol Intensivmed 1998;33(06):353–61. doi:10.1055/s-2007-994263.
10. VandenBerg KA. Individualized developmental care for high risk newborns in the NICU: A practice guidline. Elsevier Ireland Ltd. 2007. doi:10.1016/j.earlhumdev.2007.03.008
11. Hyttel-Sorensen S1, Austin T, van Bel F, Benders M, Claris O, Dempsey E, et al. A phase II randomized clinical trial on cerebral near-infrared spectroscopy plus a treatment guideline versus treatment as usual for extremely preterm infants during the first three days of life (SafeBoosC): study protocol for a randomized controlled trial. Trials 2013 May 1;14:120. doi:10.1186/1745-6215-14-120.
Science Citation Index Expanded (SciSearch) The Science Citation Index (SCI) is a citation index originally produced by the Institute for Scientific Information (ISI) and created by Eugene Garfield. It (Science Citation Index Expanded) covers more than 8,500 notable and significant journals, across 150 disciplines in science and technology, from 1900 to the present.
Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.
Chemical Abstracts Service Source Index The CAS Source Index (CASSI) Search Tool is an online resource that can quickly identify or confirm journal titles and abbreviations for publications indexed by CAS since 1907, including serial and non-serial scientific and technical publications.
IndexCopernicus The Index Copernicus International (ICI) Journals database’s is an international indexation database of scientific journals. It covered international scientific journals which divided into general information, contents of individual issues, detailed bibliography (references) sections for every publication, as well as full texts of publications in the form of attached files (optional). For now, there are more than 58,000 scientific journals registered at ICI.
Geneva Foundation for Medical Education and Research The Geneva Foundation for Medical Education and Research (GFMER) is a non-profit organization established in 2002 and it works in close collaboration with the World Health Organization (WHO). The overall objectives of the Foundation are to promote and develop health education and research programs.
Scopus Scopus is Elsevier's abstract and citation database launched in 2004. Scopus covers nearly 36,377 titles (22,794 active titles and 13,583 Inactive titles) from approximately 11,678 publishers, of which 34,346 are peer-reviewed journals in top-level subject fields: life sciences, social sciences, physical sciences and health sciences.
Embase Embase (often styled EMBASE for Excerpta Medica dataBASE), produced by Elsevier, is a biomedical and pharmacological database of published literature designed to support information managers and pharmacovigilance in complying with the regulatory requirements of a licensed drug.