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Cardiac surgery and sepsis in postoperative period – our experience

  • VIŠNJA IVANČAN1
  • MARIO PAVLEK1
  • ŽELJKO ČOLAK1
  • RAJKA GABELICA1
  • MIRABEL MAŽAR1
  • SANJA KONOSIĆ1
  • GORDANA RAJSMAN1
  • SANDRA UZUN1

1Zagreb University Clinical Hospital Centre – KBC Zagreb, Clinic of Anaesthesiology, Reanimatology and Intensive Care, Department of Anaesthesiology and Intensive Care for Cardiac Surgery Patients, Zagreb, Croatia

DOI: 10.22514/SV112.062016.9 Vol.11,Issue S2,June 2016 pp.44-46

Published: 14 June 2016

*Corresponding Author(s): VIŠNJA IVANČAN E-mail: vivancan@gmail.com

Abstract

The occurrence of sepsis after cardiac surgery is a rare event; however, its oc-currence showed catastrophic clinical outcomes. The high morbidity and mor-tality revealed the need to improve treat-ment, aiming at patients’ better clinical outcome.

Patients that develop sepsis, regardless of the infectious focus and the subjacent dis-ease, present high morbidity and mortali-ty, which vary from 17% to 65%. The main predictors of infections in the postopera-tive period are: body mass index ≥40kg/m², haemodialysis in the preoperative period, pre-op cardiogenic shock, age ≥80 years, pre-op treatment with immunosup-pressive agents, diabetes mellitus, ECC time ≥200 minutes, mechanical circula-tory support, three or more revascular-ized vessels.

From January 2015 to December 2015, we studied 675 adult patients who underwent cardiac surgery. Prophylactic antibiotic therapy was prescribed and given accord-ing to our protocol, from the induction of anaesthesia to the first postoperative day. Sepsis in the postoperative period was defined as evidence on infection associ-ated with two or more criteria of systemic inflammatory response syndrome: body temperature >38°C or <36°C, leukocytes >12,000 cells/mm³, positive blood cul-tures, respiratory rate >20/min, heart rate>100/min.

Keywords

sepsis, postoperative period, cardiac surgery

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VIŠNJA IVANČAN,MARIO PAVLEK,ŽELJKO ČOLAK,RAJKA GABELICA,MIRABEL MAŽAR,SANJA KONOSIĆ,GORDANA RAJSMAN,SANDRA UZUN. Cardiac surgery and sepsis in postoperative period – our experience. Signa Vitae. 2016. 11(S2);44-46.

References

1. Silva E, Fernandes Jr CJ, Akamine N, Sogayar AMCB, Knobel E. Sepse e choque séptico. In: Knobel E. Condutas no paciente grave. 3ª ed. São Paulo: Editora Atheneu; 2006. p. 61-78.

2. Fowler VG, O`Brain SJ, Muhlbaier LH, Corey GH, Ferguson BT, Peterson ER. Clinical predictors of major infections after cardiac surgery. Circulation. 2005;(1):112: I358-I365.

3. Slaughter MS, Olson MM, Lee JT Jr, Ward HB. A fifteen years wound surveillance study after coronary artery bypass. Ann Thorac Surg. 1993;56(5):1063-1068.

4. Toumpoulis IK, Anagnostopoulus CE, Toumpuolis SK, De Rose Jr JJ, Swistel DG. Risk factors for sepsis and endocarditis and long-term survival following coronary artery bypass grafting. World J Surg. 2005;29(5):621-627.

5. Michalopoulos A, Stavridis G, Geroulanos S. Severe sepsis in cardiac surgical patients. Eur J Surg. 1998;164: 217-222.

6. Dellinger RF, Levy MM, Carlet JM, Bion J, Parker MM, Jaeschke R, et al. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med. 2008;36(1):296-327.

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