Renal denervation in patients with resistant hypertension - single centre report
1Department of Internal Medicine, University Hospital Merkur, Zagreb, Croatia
2Zagreb University School of Medicine, Zagreb, Croatia
3Department of Radiology, Merkur Clinical Hospital, Zagreb, Croatia
DOI: 10.22514/SV101.062015.8 Vol.10,Issue S1,June 2015 pp.32-34
Published: 22 June 2015
Among patients with resistant hyperten-sion, it is very important to select patients most likely to benefit from renal sympa-thetic denervation, because they represent a very mixed group of diagnoses.
Prior to diagnosing a patient as having resistant hypertension, it is important to document adherence and exclude white-coat hypertension, inaccurate measure-ments of blood pressure and secondary causes of hypertension.
Renal sympathetic denervation has been demonstrated as an antihypertensive treat-ment in resistant hypertension patients with additional positive effects on glucose metabolism and insulin sensitivity in type 2 diabetes.
We report a single centre report of renal sympathetic denervation effects in a small cohort of patients with resistant hyperten-sion and stage 2-3 chronic kidney disease. Blood pressure reduction after renal sym-pathetic denervation was sustained at con-secutive follow-up visits one, three and six months when compared to the baseline: office systolic blood pressure was signifi-cantly lower (144 ± 13, 140 ± 17, 141 ± 15 mmHg, p<0.001).
Randomized clinical trials are required to assess the impact of the reported changes.
resistant hypertension, stepwise screening protocol, renal denervation
INGRID PRKAČIN,GORDANA CAVRIĆ,BORNA VRHOVEC,ANA LEGOVIĆ,PETRA DRAŽIĆ,VESNA ĐERMANOVIĆ DOBROTA,IVA BORAS,VINKO VIDJAK. Renal denervation in patients with resistant hypertension - single centre report. Signa Vitae. 2015. 10(S1);32-34.
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