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Case Report

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Acute respiratory distress syndrome in an 11-month-old girl leading to extracorporeal membrane oxygenation

  • ARIJAN VERBIĆ1
  • KRISTINA LAH TOMULIĆ1
  • NEVEN FRLETA1
  • IGOR MEDVED2
  • JADRANKO SOKOLIĆ3
  • ŽELJKO ŽUPAN3

1Intensive Care Unit, Department of Paediatrics, Clinical Hospital Centre Rijeka, Croatia

2Department of Cardiac Surgery, Clinical Hospital Centre Rijeka, Croatia

3Department of Anaesthesiology and Intensive Care, Clinical Hospital Centre Rijeka, Croatia

DOI: 10.22514/SV101.062015.22 Vol.10,Issue S1,June 2015 pp.74-76

Published: 22 June 2015

*Corresponding Author(s): ARIJAN VERBIĆ E-mail: arijan.verbic@gmail.com

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Abstract

Acute respiratory distress syndrome (ARDS) is a condition recognised for al-most fifty years, and is related to high mor-bidity and mortality in children. From its recognition, medical experts tried to make joint efforts to make recommendations and optimize treatment in children and adult population. The new definition of ARDS suggests treatment by introducing three levels of severity, according to PaO2/FiO2 and positive end-expiratory pres-sure. Lung-protective ventilation remains crucial in achieving better outcome in pae-diatric acute respiratory distress syndrome (PARDS), but promising therapies based on paediatric studies include non-invasive ventilation, endotracheal surfactant, high-frequency oscillatory ventilation (HFOV), and use of ECMO as „rescue“ therapy. Nevertheless, PARDS is a real challenge for the paediatric critical care provider, and even if current state-of-the-art treatment methods are delivered, this disease often leads to fatal outcome. 

We report the case of an 11-month-old female infant who developed ARDS, was treated by current up-to-date treatment methods, including ECMO, and despite this, succumbed to her illness. With this case report we would like once more to bring to consideration the current knowl-edge on etiology, epidemiology, diagnosis and treatment of ARDS in children, and emphasize the high morbidity and mortal-ity related to this syndrome.

Key words

Acute respiratory distress syn-drome (ARDS), children, paediatric, extra-corporeal membrane oxygenation (ECMO)

Cite And Share

ARIJAN VERBIĆ,KRISTINA LAH TOMULIĆ,NEVEN FRLETA,IGOR MEDVED,JADRANKO SOKOLIĆ,ŽELJKO ŽUPAN. Acute respiratory distress syndrome in an 11-month-old girl leading to extracorporeal membrane oxygenation. Signa Vitae. 2015. 10(S1);74-76.

References

1. Koh Y: Update in acute respiratory distress syndrome. Journal of Intensive Care 2014, 2:2

2. Cornfield DN et al.: Acute respiratory distress syndrome in children: physiology and management. Curr Opin Pediatr. 2013 Jun;25(3):338-43

3. Ranieri VM, Rubenfeld GD, Thompson BT, et al: Acute respiratory distress syndrome: The Berlin definition. JAMA 2012; 307:2526–2533

4. The Pediatric Acute Lung Injury Consensus Conference Group: Pediatric Acute Respiratory Distress Syndrome: Consensus Rec-ommendations From the Pediatric Acute Lung Injury Consensus Conference. Pediatr Crit Care Med. 2015 Feb 2

5. Extracorporeal Life Support Organization. Available from: URL: http: //www.elsonet.org. Accessed 03-19-2013

6. Maslach-Hubbard A, Bratton SL: Extracorporeal membrane oxygenation for pediatric respiratory failure: History, development and current status. World J Crit Care Med 2013 November 4; 2(4): 29-39

7. Zabrocki LA, Brogan TV, Statler KD, Poss WB, Rollins MD, Bratton SL. Extracorporeal membrane oxygenation for pediatric res-piratory failure: Survival and predictors of mortality. Crit Care Med 2011; 39: 364-370

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