Signa Vitae

Print ISSN: 1334-5605 | Online ISSN: 1845-206X

Official journal of the International Women in Intensive and critical care Network (iWIN, https://www.iwinideal.com/home/)

Signa Vitae (SV) is a peer-reviewed, open-access journal that aims to be an unbiased and permanent forum for the fields of emergency medicine, intensive care medicine, anesthesia and pain medicine. It focuses on the latest research advances in these fields, including Disease prevention, diagnose, treatment and prognosis, Disease etiology, pathophysiology, and molecular mechanisms, Health care, Medical personnel health, Facilities and equipment, Teaching and training, Organization and management, Information and techniques, Drug application, etc. As a tool for easier and more effective experiences and science sharing, SV aims to provide professionals dedicated to all these relevant fields with cutting-edge techniques and information.



Articles

Open Access

Too soon to deflate? Rethinking IABP in the era of Altshock-2

Maks Mihalj,Charles Wanna,Sriram Nathan,Harish Devineni,Alessandro Belletti,Anna Mara Scandroglio,Igor D. Gregoric,Angelo Nascimbene,Biswajit Kar

DOI: 10.22514/sv.2025.189

Abstract ( 349 ) PDF (152.12 kB) ( 32 ) Full Text

Open Access

Antifibrotic therapy in patients with acute lung injury: a systematic review and meta-analysis

Nora Di Tomasso,Valentina Ajello,Gianluca Paternoster,Daniele Orso,Carolina Soledad Romero Garcia,Laura Pasin,Filippo D’Amico,Luigi Beretta,Alberto Zangrillo,Giacomo Monti,PIONEER study group

DOI: 10.22514/sv.2025.163

Abstract ( 978 ) PDF (2.65 MB) ( 45 ) Full Text

Open Access

Aspartate aminotransferase to platelet ratio index as a predictor of mortality in traumatic brain injury

Ching-Ya Huang,Ching-Hua Tsai,Wei-Ti Su,Shiun-Yuan Hsu,Ching-Hua Hsieh

DOI: 10.22514/sv.2025.155

Abstract ( 757 ) PDF (1.46 MB) ( 29 ) Full Text

Open Access

Evaluating sarcopenia in emergency department triage: implications for hospitalization and critical care

Li-Chin Chen,Chip-Jin Ng,Chin-Yen Han,Cheng-Yu Chien,Shu-Yu Kuo

DOI: 10.22514/sv.2025.162

Abstract ( 779 ) PDF (4.91 MB) ( 31 ) Full Text

Open Access

Characteristics and outcomes of patients with solid tumors admitted to the intensive care unit in Saudi Arabia

Abdullah M. Alhammad,Saleh S. Alzahrani,Lama T. Almutairi,Mohammad H. Aljawadi,Reema H. Alfehaid,Alaa Z. Alhajjari,Nora A. Alkhudair,Rakan M. Alqahtani,Fadi S. Aljamaan,Khalid A. Al Sulaiman,Rashid K. Alballaa,Mohammad A. Alghamdi,Mohammed I. Alarifi

DOI: 10.22514/sv.2025.158

Abstract ( 785 ) PDF (341.49 kB) ( 21 ) Full Text

Open Access

A modified risk model for upper gastrointestinal bleeding: comparative evaluation of the H3B2A1 score

Meliha Fındık,Muhammet Çakas,Ahmet Buğra Önler,Murat Başcı,Selman Gümüş,Ramazan Kıyak

DOI: 10.22514/sv.2025.180

Abstract ( 650 ) PDF (1.93 MB) ( 25 ) Full Text

Open Access

Can CALLY score predict mortality and ICU stay in elderly patients with sepsis?

Ayşe Begum Çakır,Gorkem Alper Solakoglu,Kerim Erim,Behcet Al

DOI: 10.22514/sv.2025.166

Abstract ( 802 ) PDF (2.47 MB) ( 28 ) Full Text

Open Access

Early predictors of acute kidney injury after Cardiac Surgery

Zinet Asuman Arslan Onuk,Gökhan Ozerdem,Sibel Kulaksızoglu,Birkan Akbulut,Fatih Metinyurt,Aysen Baysan,Levent Donmez

DOI: 10.22514/sv.2025.153

Abstract ( 1009 ) PDF (4.31 MB) ( 29 ) Full Text

Open Access

Frontal QRS-T angle and mortality in ischemic stroke patients: a multicenter study

Murat Genç,Didem Çankaya Gökdere,Adil Emre Gezer,Melih Çamcı,Bensu Bulut,Medine Akkan Öz,Ramiz Yazıcı,Huseyin Mutlu,Zekeriya Uykan

DOI: 10.22514/sv.2025.194

Abstract ( 271 ) PDF (6.16 MB) ( 24 ) Full Text

Published Ahead of Print

Open Access

Impact of the interval between cardiopulmonary resuscitation and veno-arterial extracorporeal membrane oxygenation on in-hospital mortality in adult patients after cardiac arrest

Qiufeng Liao,Qi Liu,Simin Li,Hailin He,Rongxing Bao,Xiaolin Gu,Chongjian Zhang

Online publish date: 12 December 2025

DOI: 10.22514/sv.2025.197

Abstract ( 122 ) PDF (2.4 MB) ( 18 ) Full Text

Open Access

Health disparities in emergency department patients with severe mental illness and non-traumatic hollow organ perforation

Shang-Kai Hung,Chung-Hsien Chaou,Shi-Ying Gao,Chiao-Hsuan Hsieh,Kai-Hsiang Wu,Hsiang-Yun Lo,Wei-Chen Chen,Shou-Yen Chen,Chih-Huang Li,Hsien-Yi Chen,Ming-Jen Huang

Online publish date: 11 December 2025

DOI: 10.22514/sv.2025.196

Abstract ( 123 ) PDF (1.13 MB) ( 12 ) Full Text

Open Access

Analysis of medical evacuation following the Tünektepe cable car accident in Turkey in 2024

Mustafa Keşaplı,Adeviyye Aksoy,Deniz Kılıç,Mehmet Fatih Gülşen

Online publish date: 03 December 2025

DOI: 10.22514/sv.2025.187

Abstract ( 356 ) PDF (3.22 MB) ( 13 ) Full Text

Open Access

Hypermagnesemia and mortality in COPD patients

Ceren Önal,Kazım Koray Özgül,Ayşe Kösem,Yalçın Şenol,Gülten Arslan

Online publish date: 03 December 2025

DOI: 10.22514/sv.2025.188

Abstract ( 344 ) PDF (589.38 kB) ( 22 ) Full Text

Open Access

Non-invasive respiratory support for postoperative acute hypoxemic respiratory failure: a narrative review

Francesco Coppolino,Pasquale Sansone,Gianluigi Cosenza,Leonardo Maria Bottazzo,Simona Brunetti,Sara De Sarno,Maurizio Del Prete,Maria Beatrice Passavanti,Marco Fiore,Clelia Esposito,Maria Caterina Pace,Vincenzo Pota

Online publish date: 28 November 2025

DOI: 10.22514/sv.2025.186

Abstract ( 493 ) PDF (308.46 kB) ( 12 ) Full Text

Open Access

Ultrasonography to measure gastric content in pregnant and nonpregnant female patients undergoing elective surgery

Semih Çelik,Engin İhsan Turan,Emirhan Kahraman,Oktay İnan,Ezgi Aydın İnan,Alican Ruşen,Ayça Sultan Şahin

Online publish date: 25 November 2025

DOI: 10.22514/sv.2025.184

Abstract ( 469 ) PDF (4.89 MB) ( 19 ) Full Text

Special Issues

Special issue title:

Optimization of Cardiovascular Dynamics in Critical Care Medicine and Anesthesiology

Keywords: Critical Care Medicine; Anesthesiology; Cardiovascular Dynamics; Hemodynamics

Editor: Prof. Dr. Athanasios Chalkias, MD, MSc, PhD, FESC, FAcadTM, FCP, FESAIC,Dr. Paraskevi Tselioti, MD, PhD

Submission deadline: 31 December 2025

Special issue title:

Acute Trauma: Immediate Interventions, Long-Term Impacts, Advancements, and Medico-legal Evaluation

Keywords: EMS; Trauma Management; Healthcare System Preparedness; Medico-Legal Evaluation

Editor: Prof. Dr. Giuseppe Basile, MD,Dr. Luca Bianco Prevot, MD,Dr. Vittorio Bolcato, MD

Submission deadline: 31 July 2026

Special issue title:

Advances in Emergency Cardiac Care

Keywords: Ischemic Heart Disease; Heart Failure; Arrhythmia; Defibrillation; PCI; Telemedicine; Resuscitation

Editor: Prof. Dr. Ozgur Karcioglu, MD, FEMAT,Assoc. Prof. Dr. Canan Akman, MD

Submission deadline: 01 March 2026

Special issue title:

Advances in the Diagnosis and Management of Sepsis and Septic Shock

Keywords: Diagnosis; Management; Sepsis; Septic Shock; Lactate Hypotension; Vasopressors

Editor: Prof. Dr. Ozgur Karcioglu, MD,Assoc. Prof. Dr. Feride Sinem AKGUN, MD,Assist. Prof. Dr. Betul AKBUGA OZEL, MD

Submission deadline: 01 May 2026

Special issue title:

2025 Annual Meeting of Taiwanese Society of Regional Anesthesia & Pain Management (TSRA-PM) in Conjunction with International Symposium of Regional Anesthesia Asia (RA Asia)

Keywords: Regional Anesthesia; Pain Medicine; Anatomy

Editor: Assoc. Prof. Dr. Jui-An Lin, MD, PhD,Assist. Prof. Dr. Kuo-Chuan Hung, MD,Enoch Yi-No Kang,Prof. Dr. Ke-Vin Chang, MD, PhD, CIPS, RMSK, ASRA-PMUC,Assoc. Prof. Dr. Wu Shao Chun, MD,Dr. Shang-Ru Yeoh, MD, MSc

Submission deadline: 01 August 2026

Special issue title:

Critical Interventions: Enhancing Emergency Medical Services through Interdisciplinary Research

Keywords: Emergency Medical Services; Interdisciplinary Research in EMS; Pre-hospital Care Technologies; Crisis Management in Healthcare; Psychological Aspects of EMS; Public Health and Emergency Services

Editor: Prof. Dr. Krzysztof Goniewicz, PhD,Prof. Dr. Ahmed M. Al-Wathinani, PhD

Submission deadline: 28 February 2025

Special issue title:

Advances in Obstetric Anaesthesia

Keywords: Obstetric Anaesthesia; Epidural Analgesia; Remifentanil-PCA; Labour and Delivery Outcomes; Quality Control in Perinatology and Obstetric Anaesthesia; ROTEM; Obstetric Haemorrhage; Preeclampsia

Editor: Prof. Tatjana Stopar Pintarič, MD, PhD, DEAA

Submission deadline: 31 December 2023

Special issue title:

Cardiothoracic anaesthesia and intensive care: current challenges and novelties

Keywords: cardiac anaesthesia, thoracic anaesthesia, intensive care, education, innovation, perioperative medicine, healthcare, outcomes, challenges

Editor: Dr. Marko Zdravkovic, MD, PhD

Submission deadline: 30 November 2022

Special issue title:

Selected papers from Korean Society of Emergency Medicine (KSEM) in 2021-2022

Keywords: Emergency medicine

Editor: Kyungwon Lee, MD, PhD,Young Duck Cho, MD, PhD

Submission deadline: 31 December 2022

Special issue title:

Medical Simulation - success in education, future of science

Keywords: medical simulation, emergency medicine, medical education

Editor: Tomasz Kłosiewicz, MD, MSc,Mateusz Puślecki, PhD

Submission deadline: 31 December 2022

To Be a Reviewer

If you would like to review a manuscript for Signa Vitae journal, please click “Review for SV” below to register at our submission website or log in our Online Peer Review system. Your name, contact details, and expertise will be automatically added to our database of reviewers.

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Join Editorial Board

You are welcome to join our editorial board. Our journal produces and issues editorial board certificates for editorial board members, and the journal website will display the names and personal websites of editorial board members to help enhance their scientific influence. Members of the editorial committee are entitled to 1 free publication (editorial member’s or recommended paper) per year, and other articles over 2 can enjoy 30% discount of publishing fee.

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Editor-in-Chief

Prof. Giovanni Landoni, MD

Prof Giovanni Landoni, MD, is currently Full Professor and Residency Program Director of Anesthesia and Intensive Care Medicine at Vita-Salute San Raffaele University, Milan, Italy. He’s also Director of the Center for Intensive Care and Anesthesiology of San Raffaele Hospital in Milan, Italy. His strong clinical and research interests in intensive care and anesthesia resulted in more than 700 scientific publications in indexed journals, cited >20,000 times, h-index=75 on Scopus and 95 on Scholar, including randomized trials on NEJM, Lancet, and JAMA, and over 100 invitations in international congresses. He participated to 47 randomized controlled trials. Prof Landoni was Chief Investigator in successfully completed multicenter randomized clinical trials that randomized > 10,000 critically ill or perioperative patients over the last 10 years. He served as reviewer for over 50 journals (NEJM, JAMA, and The Lancet among others) and for foreign grant agencies, and he is member of the Editorial Board of several international journals.