Signa Vitae

Print ISSN: 1334-5605 | Online ISSN: 1845-206X

Signa Vitae (SV) is a peer-reviewed, open-access journal that aims to be an unbiased and permanent forum for the fields of emergency medicine, intensive care medicine, anesthesia and pain medicine. It focuses on the latest research advances in these fields, including Disease prevention, diagnose, treatment and prognosis, Disease etiology, pathophysiology, and molecular mechanisms, Health care, Medical personnel health, Facilities and equipment, Teaching and training, Organization and management, Information and techniques, Drug application, etc. As a tool for easier and more effective experiences and science sharing, SV aims to provide professionals dedicated to all these relevant fields with cutting-edge techniques and information.



Early postoperative cognitive decline—are there any preventive strategies for surgical patients in the emergency setting?

Articles

Open Access

Remote ischemic preconditioning in non-cardiac surgery (PRINCE): a multinational, double blind, sham-controlled, randomized clinical trial

Massimiliano Greco,Gaetano Lombardi,Aidos Konkayev,Claudia Brusasco,Chong Lei,Agostino Roasio,Nerlep Rana,Hugo A. Mantilla-Gutierrez,Marco Micali,Gordana Gazivoda,Michela Gandini,Lian Kah Ti,Stefano Bosso,Maiya Konkayeva,Francesco Meroi,Lini Wang,Andrea Russo,Sergey Efremov,Giuseppe Fresta,Levan Berikashvili,Francesca Livi,Ivan Šitum,Fabio Guarracino,Elizaveta Leonova,Francesca Cavenago,Maria Shemetova,Edoardo Cristallo,Anastasia Smirnova,Lorenzo Schiavoni,Valerii Subbotin,Nicoletta Boffa,Giuseppe Giardina,Michele Introna,Cristina Nakhnoukh,Remo Daniel Covello,Marina Pieri,Stefano Turi,Valentina Ajello,Fabrizio Monaco,Francesco Corradi,Andrey Yavorovskiy,Valery Likhvantsev,Federico Longhini,Tiziana Bove,Rinaldo Bellomo,Giovanni Landoni,Alberto Zangrillo,Rosalba Lembo

DOI: 10.22514/sv.2024.151

Abstract ( 655 ) PDF (8.98 MB) ( 177 ) Full Text

Open Access

AI-based cancer pain assessment through speech emotion recognition and video facial expressions classification

Marco Cascella,Francesco Cutugno,Fabio Mariani,Vincenzo Norman Vitale,Manuel Iuorio,Arturo Cuomo,Sabrina Bimonte,Valeria Conti,Francesco Sabbatino,Alfonso Maria Ponsiglione,Jonathan Montomoli,Valentina Bellini,Federico Semeraro,Alessandro Vittori,Elena Giovanna Bignami,Ornella Piazza

DOI: 10.22514/sv.2024.153

Abstract ( 449 ) PDF (11.11 MB) ( 164 ) Full Text

Open Access

Prehospital management of hypertension by emergency medical teams during the COVID-19 pandemic: a retrospective analysis

Adrian Moskal,Sebastian Kowalski,Karolina Żak-Kowalska,Ahmed M. Al-Wathinani,Krzysztof Goniewicz,Mariusz Goniewicz

DOI: 10.22514/sv.2024.154

Abstract ( 817 ) PDF (212.76 kB) ( 130 ) Full Text

Open Access

Comparative analysis of the efficacy and safety of hydromorphone and sufentanil as postoperative analgesia in children: a double-blind, prospective, randomized, and multicentered controlled trial

Yongying Pan,Baisong Zhao,Xinggang Ma,Ligang Meng,Qingren Liu,Junjie Huang,Wenqi Huang,Lijun Niu,Dianqing Cao,Zhenyi Yan,Pei Liu,Ting Yan,Dexing Luo,Xin Guo,Yan Li,Xiaohong Chen,Xingrong Song

DOI: 10.22514/sv.2024.156

Abstract ( 433 ) PDF (3.77 MB) ( 156 ) Full Text

Open Access

Esmolol as a cardioprotective agent to reduce low cardiac output syndrome after cardiac surgery

Giuseppe Crescenzi,Lucia Torracca,Michele Danilo Pierri,Filippo Capestro,Concetta Rosica,Federico Mattia Oliva,Giovanni Landoni

DOI: 10.22514/sv.2024.157

Abstract ( 455 ) PDF (2.71 MB) ( 128 ) Full Text

Open Access

Astragaloside IV improves myocardial injury in rats with insulin-resistant heart failure

Yaoyao Wang,Yujiang Chen,Tengxian Li,Peng Zhong,Qinsha Wang

DOI: 10.22514/sv.2024.158

Abstract ( 425 ) PDF (8.45 MB) ( 149 ) Full Text

Open Access

Diagnostic value of asprosin for sepsis: a case-control study in the emergency department

Emre Bülbül,İbrahim Toker,Ahu Cephe,Muhammed Ali Gençaslan,Zeynep Türe Yüce,Sabahattin Muhtaroğlu,Gökmen Zararsız

DOI: 10.22514/sv.2024.159

Abstract ( 450 ) PDF (1.29 MB) ( 128 ) Full Text

Open Access

Knockdown of ORM2 improves cerulein-induced acute pancreatitis in vitro via the p38 MAPK signaling pathway

Jie Du,Chuanming Zheng,Taizhe Zhang,Sandang Li,Zhong Ji,Zhenjie Wang

DOI: 10.22514/sv.2024.160

Abstract ( 444 ) PDF (6.04 MB) ( 110 ) Full Text

Open Access

Predictive value of serum and urinary neutrophil gelatinase-associated lipocalin in the early detection of acute kidney injury after major abdominal surgery

Erhan Ozyurt,Mehmet Tercan,Orhan Aras,Ridvan Yavuz,Huseyin Ciyiltepe,Tebessum Cakir,Guzin Aykal,Nilgun K Ozturk

DOI: 10.22514/sv.2024.133

Abstract ( 824 ) PDF (4.33 MB) ( 193 ) Full Text

Open Access

Successful extracorporeal cardiopulmonary resuscitation in a refractory out-of-hospital cardiac arrest after ethylene glycol poisoning

Peter Sklienka,Jan Neiser,Juraj Rodina,Filip Burša,Jan Máca,Michal Frelich,Tomáš Jonszta

DOI: 10.22514/sv.2024.164

Abstract ( 395 ) PDF (212.62 kB) ( 141 ) Full Text

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Published Ahead of Print

Open Access

Predictive value of inflammatory indices in acute cholecystitis: a retrospective study of gallstone detection and outcome assessment

Mehmet Göktuğ Efgan,Ejder Saylav Bora,Semih Musa Coşkun,Süleyman Kırık,Ahmet Kayalı

Online publish date: 12 October 2024

DOI: 10.22514/sv.2024.134

Abstract ( 681 ) PDF (4.86 MB) ( 179 ) Full Text

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Development of a real-time monitoring and detection indoor air quality system for intensive care unit and emergency department

Special Issues

Special issue title:

Optimization of Cardiovascular Dynamics in Critical Care Medicine and Anesthesiology

Keywords: Critical Care Medicine; Anesthesiology; Cardiovascular Dynamics; Hemodynamics

Editor: Prof. Dr. Athanasios Chalkias, MD, MSc, PhD, FESC, FAcadTM, FCP, FESAIC,Dr. Paraskevi Tselioti, MD, PhD

Submission deadline: 31 December 2025

Special issue title:

Critical Interventions: Enhancing Emergency Medical Services through Interdisciplinary Research

Keywords: Emergency Medical Services; Interdisciplinary Research in EMS; Pre-hospital Care Technologies; Crisis Management in Healthcare; Psychological Aspects of EMS; Public Health and Emergency Services

Editor: Prof. Dr. Krzysztof Goniewicz, PhD,Prof. Dr. Ahmed M. Al-Wathinani, PhD

Submission deadline: 28 February 2025

Special issue title:

AI Horizons: Revolutionizing Anesthesia, Critical Care, and Pain Medicine

Keywords: Anesthesia; Critical Care Medicine; Pain Medicine; Artificial Intelligence; Large Language Models; Natural Language Processing; Big Data; Data Science; Machine Learning

Editor: Prof. Marco Cascella

Submission deadline: 31 December 2024

Special issue title:

Advances in Obstetric Anaesthesia

Keywords: Obstetric Anaesthesia; Epidural Analgesia; Remifentanil-PCA; Labour and Delivery Outcomes; Quality Control in Perinatology and Obstetric Anaesthesia; ROTEM; Obstetric Haemorrhage; Preeclampsia

Editor: Prof. Tatjana Stopar Pintarič, MD, PhD, DEAA

Submission deadline: 31 December 2023

Special issue title:

Cardiothoracic anaesthesia and intensive care: current challenges and novelties

Keywords: cardiac anaesthesia, thoracic anaesthesia, intensive care, education, innovation, perioperative medicine, healthcare, outcomes, challenges

Editor: Dr. Marko Zdravkovic, MD, PhD

Submission deadline: 30 November 2022

Special issue title:

Selected papers from Korean Society of Emergency Medicine (KSEM) in 2021-2022

Keywords: Emergency medicine

Editor: Kyungwon Lee, MD, PhD,Young Duck Cho, MD, PhD

Submission deadline: 31 December 2022

Special issue title:

Medical Simulation - success in education, future of science

Keywords: medical simulation, emergency medicine, medical education

Editor: Tomasz Kłosiewicz, MD, MSc,Mateusz Puślecki, PhD

Submission deadline: 31 December 2022

Special issue title:

21st Panhellenic Congress on Regional Anaesthesia, Pain Management and Palliative Care

Keywords: Regional Anaesthesia, Pain Management, Palliative Care, PARH.SY.A., ESRA HELLAS, the A’ Anaesthesiology Department, Faculty of Medicine, University of Athens

Editor: Dr. Ioanna Siafaka, MD, PhD,Dr. Maria Kokolaki, MD, PhD,Dr. Athina Vadalouca, MD, PhD, FIPP,Dr. Evmorfia Stavropoulou, MD, PhD, EDRA,Dr. Eleni Moka, MD, PhD, MSc, EDRA

Submission deadline: 27 May 2022

Special issue title:

Selected papers from Korean Association of Cardiopulmonary Resuscitation in 2021

Keywords: Cardiac arrest, Resuscitation, cardiopulmonary resuscitation, guidelines, outcome

Editor: Prof. Won Young Kim, MD, PhD

Submission deadline: 01 June 2022

Special issue title:

Spinal Cord Injury

Keywords: Spinal cord injury (SCI), Damage mechanisms, Primary and secondary medullary lesions, Neurorehabilitation, Neurorestoration

Editor: Lecturer dr. Constantin Munteanu, PhD,Prof. Dr. Gelu Onose,Associate Prof. Dr. Mariana Rotariu, PhD,Assistant Prof. Dr. Gabriela Dogaru, PhD,Associate Prof. Dr. Elena Valentiana IONESCU, PhD,Assistant Prof. Dr. Cristina Daia, PhD

Submission deadline: 31 March 2022

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If you would like to review a manuscript for Signa Vitae journal, please click “Review for SV” below to register at our submission website or log in our Online Peer Review system. Your name, contact details, and expertise will be automatically added to our database of reviewers.

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Join Editorial Board

You are welcome to join our editorial board. Our journal produces and issues editorial board certificates for editorial board members, and the journal website will display the names and personal websites of editorial board members to help enhance their scientific influence. Members of the editorial committee are entitled to 1 free publication (editorial member’s or recommended paper) per year, and other articles over 2 can enjoy 30% discount of publishing fee.

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Editor-in-Chief

Prof. Giovanni Landoni, MD

Prof Giovanni Landoni, MD, is currently Full Professor and Residency Program Director of Anesthesia and Intensive Care Medicine at Vita-Salute San Raffaele University, Milan, Italy. He’s also Director of the Center for Intensive Care and Anesthesiology of San Raffaele Hospital in Milan, Italy. His strong clinical and research interests in intensive care and anesthesia resulted in more than 700 scientific publications in indexed journals, cited >20,000 times, h-index=75 on Scopus and 95 on Scholar, including randomized trials on NEJM, Lancet, and JAMA, and over 100 invitations in international congresses. He participated to 47 randomized controlled trials. Prof Landoni was Chief Investigator in successfully completed multicenter randomized clinical trials that randomized > 10,000 critically ill or perioperative patients over the last 10 years. He served as reviewer for over 50 journals (NEJM, JAMA, and The Lancet among others) and for foreign grant agencies, and he is member of the Editorial Board of several international journals.