Deadline for manuscript submissions: 15 September 2021Print Special Issue Flyer (5)
Attending doctor, Lecturer, Department of Rehabilitation Medicine, Clinical Medical College and The First Affiliated Hospital of Chengdu Medical College, Chengdu, China
Interests: Neurological rehabilitation, Cardiovascular rehabilitation, Hyperbaric oxygen medicine
Acute CO poisoning is the most common type of acute poisoning worldwide, and about 40 % of surviving patients develop delayed encephalopathy after acute carbon monoxide poisoning (DEACMP). The symptoms of DEACMP include impaired judgment, poor concentration and memory, cognitive dissonance, personality changes, psychosis, and even Parkinsonism symptoms. To date, the mechanisms of DEACMP remain unclear.
Exosomes are a heterogeneous group of nano-sized natural membrane vesicle released from various cells and exist in body fluids. A growing amount of evidence shows that exosomes involve in pathogenesis, diagnosis and treatment modalities of some brain disease, such as ischemic stroke, Alzheimer's disease, Parkinson disease, multiple sclerosis, brain cancers, and so on. In the light of exosomes can overcome the blood-brain barrier (BBB), exosomes as therapeutic drug carrier for brain drug delivery, have received extensive attention.
Previous studies suggested that DEACMP may be the outcome of acute CO poisoning induced cerebral cellular hypoxia, postischemic reperfusion injury, free radical damage, immune damage, and apoptosis. The secretion of exosomes by cerebral cells is mediated by various physical, chemical, and biological stimuli such as hypoxia, low pH, extracellular ATP, increased intracellular Ca2+, and DNA damage. Therefore, the potential roles of exosomes in pathogenesis and prognosis of DEACMP is worth deep exploration.
In this issue we welcome original research articles and reviews on this topic to provide recent findings and explore diverse functions of exosomes in DEACMP.
Acute CO poisoning, DEACMP, Exosomes
Manuscripts should be submitted online by submit system. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Original articles, case reports or comprehensive reviews are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website. Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Signa Viate is an international peer-reviewed open access semi-annual journal published by MRE Press. Please visit the Instructions for Authors page before submitting a manuscript.The Article Processing Charge (APC) for publication in this open access journal is $1200. We normally offer a discount greater than 30% to all contributors invited by the Editor-in-Chief, Guest Editor (GE) and Editorial board member. Submitted papers should be well formatted and use good English.
Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,200 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.
Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.
Chemical Abstracts Service Source Index The CAS Source Index (CASSI) Search Tool is an online resource that can quickly identify or confirm journal titles and abbreviations for publications indexed by CAS since 1907, including serial and non-serial scientific and technical publications.
IndexCopernicus The Index Copernicus International (ICI) Journals database’s is an international indexation database of scientific journals. It covered international scientific journals which divided into general information, contents of individual issues, detailed bibliography (references) sections for every publication, as well as full texts of publications in the form of attached files (optional). For now, there are more than 58,000 scientific journals registered at ICI.
Geneva Foundation for Medical Education and Research The Geneva Foundation for Medical Education and Research (GFMER) is a non-profit organization established in 2002 and it works in close collaboration with the World Health Organization (WHO). The overall objectives of the Foundation are to promote and develop health education and research programs.
Scopus Scopus is Elsevier's abstract and citation database launched in 2004. Scopus covers nearly 36,377 titles (22,794 active titles and 13,583 Inactive titles) from approximately 11,678 publishers, of which 34,346 are peer-reviewed journals in top-level subject fields: life sciences, social sciences, physical sciences and health sciences.
Embase Embase (often styled EMBASE for Excerpta Medica dataBASE), produced by Elsevier, is a biomedical and pharmacological database of published literature designed to support information managers and pharmacovigilance in complying with the regulatory requirements of a licensed drug.