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Original Research

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Outcome of liver transplant patients at the University Hospital Centre Zagreb

  • ANA VUJAKLIJA BRAJKOVIĆ1
  • JAKŠA BABEL1
  • VESNA VEGAR2
  • MARINA PREMUŽIĆ3
  • DAVOR RADIĆ3
  • VLADIMIR GAŠPAROVIĆ1

1Department of Intensive Care Medicine, University Hospital Centre Rebro, Kispaticeva 12, Zagreb 10 000, Croatia

2Department of Anaesthesiology, Reanimatology and Intensive Care, University Hospital Centre Rebro, Kispaticeva 12, Zagreb 10 000, Croatia

3Department of Gastroenterology, University Hospital Centre Rebro, Kispaticeva 12, Zagreb 10 000, Croatia

DOI: 10.22514/SV101.062015.12 Vol.10,Issue S1,June 2015 pp.47-49

Published: 22 June 2015

*Corresponding Author(s): ANA VUJAKLIJA BRAJKOVIĆ E-mail: avujaklija@gmail.com

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Abstract

At the University Hospital Centre Zagreb, 37 patients underwent liver transplanta-tion in the period from 2010 to 2014. Six patients had fatal complications in the ear-ly post-transplantation period and deceas-es in the surgical intensive care unit (ICU). All other patients (31) were transferred to the medical ICU and later to the medical ward. The most common indications for liver transplantation were alcoholic liver disease (9 patients) and hepatitis C (8 pa-tients). Two-thirds of the patients were male (67.7%) with an average age of 51 years. Thirty patients were discharged alive from the hospital. Infections developed in nine patients, mostly pneumonia and peritonitis. Only one patient experienced infection caused by multi-drug resistant bacteria, namely peritonitis due to me-thicillin-resistant Staphylococcus aureus (MRSA). All infections were successfully treated with antibiotics and none of them caused graft rejection.

Key words

liver transplantation, infection, outcome assessment

Cite And Share

ANA VUJAKLIJA BRAJKOVIĆ,JAKŠA BABEL,VESNA VEGAR,MARINA PREMUŽIĆ,DAVOR RADIĆ,VLADIMIR GAŠPAROVIĆ. Outcome of liver transplant patients at the University Hospital Centre Zagreb. Signa Vitae. 2015. 10(S1);47-49.

References

1. Heidelbaugh JJ, Bruderly M. Cirrhosis and chronic liver failure: part I. Diagnosis and evaluation. Am Fam Physician 2006; 74:756.

2. Kim SI. Bacterial infection after liver transplantation. World J Gastro¬enterol. 2014;20:6211–6220.

3. Fishman JA. Infections in immunocompromised hosts and organ transplant recipients: essentials. Liver Transpl 2011; 17 Suppl 3: S34-S37 [PMID: 21748845 DOI: 10.1002/lt.22378

4. Shi SH, Kong HS, Xu J, Zhang WJ, Jia CK, Wang WL, Shen Y, Zhang M, Zheng SS. Multidrug resistant Gram-negative bacilli as predominant bacteremic pathogens in liver transplant recipients. Transpl Infect Dis. 2009 Oct;11(5):405-12

5. Dummer JS, Singh N. Infections in solid organ transplant recipients. In: Mandell GL, Bennett JE, Dolin R. Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, PA: Churchill Livingstone, 2010: 3839-3850

6. Weiss E, Dahmani S, Bert F, Janny S, Sommacale D, Dondero F, Francoz C, Belghiti J, Mantz J, Paugam-Burtz C. Earlyonset pneumonia after liver transplantation: microbiological findings and therapeutic consequences. Liver Transpl 2010; 16: 1178-1185 [PMID: 20879016 DOI: 10.1002/lt.22132

7. Paya CV, Hermans PE. Bacterial infections after liver transplantation. Eur J Clin Microbiol Infect Dis 1989; 8: 499-504 [PMID: 2504588]).

8. García Prado ME, Matia EC, Ciuro FP, Díez-Canedo JS, Sousa Martín JM, Porras López FM, de la Casa AC, Cisneros Herreros JM. Surgical site infection in liver transplant recipients: impact of the type of perioperative prophylaxis. Transplantation. 2008;85:1849–1854

9. Wade JJ, Rolando N, Hayllar K, Philpott-Howard J, Casewell MW, Williams R. Bacterial and fungal infections after liver transplan-tation: an analysis of 284 patients. Hepatology. 1995;21:1328–1336

10. Kusne S, Dummer JS, Singh N, Iwatsuki S, Makowka L, Esquivel C, Tzakis AG, Starzl TE, Ho M. Infections after liver transplanta-tion. An analysis of 101 consecutive cases. Medicine (Baltimore) 1988;67:132–143.

11. Kusne S, Dummer JS, Singh N, et al. Infections after liver transplanta¬tion. An analysis of 101 consecutive cases. Medicine (Balti-more). 1988;67:132–143

12. Soong RS, Chan KM, Chou HS, et al. The risk factors for early infection in adult living donor liver transplantation recipients. Transplant Proc. 2012;44:784–786.

13. Kim YJ, Kim SI, Wie SH, Kim YR, Hur JA, Choi JY, Yoon SK, Moon IS, Kim DG, Lee MD, Kang MW. Infectious complications in living-donor liver transplant recipients: a 9-year single-center experience. Transpl Infect Dis 2008; 10: 316-324 [PMID: 18507752 DOI: 10.1111/j.1399-3062.2008.00315.x

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